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Protein

Thymidine kinase

Gene

BP951000_1592

Organism
Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:BP951000_1592Imported
OrganismiBrachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)Imported
Taxonomic identifieri759914 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesBrachyspiralesBrachyspiraceaeBrachyspira
Proteomesi
  • UP000000332 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi759914.BP951000_1592.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000096068.
KOiK00857.
OMAiIYSKRIV.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

D8IEK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAGKSKYLI KTLDYLLMEK SDIKILFIYP NISYRGYFCR DKNVVFDKRI
60 70 80 90 100
DIITEEELED KFTNIENYLS NYDVVGIDEF CFLNKTSEFI KLIKDFSRNN
110 120 130 140 150
INIDFYIASL DMDFKRNYWE SVSSLIEEDL IDVHIKVFGK CDCGRKGIYS
160 170 180
KRIVKDVDRI VIGDDIYKCV CRYCYEGEDE VKLNL
Length:185
Mass (Da):21,984
Last modified:October 5, 2010 - v1
Checksum:i0FBE38688FEA14C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002025 Genomic DNA. Translation: ADK31573.1.

Genome annotation databases

EnsemblBacteriaiADK31573; ADK31573; BP951000_1592.
KEGGibpo:BP951000_1592.
PATRICi42197619. VBIBraPil164347_1563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002025 Genomic DNA. Translation: ADK31573.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi759914.BP951000_1592.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADK31573; ADK31573; BP951000_1592.
KEGGibpo:BP951000_1592.
PATRICi42197619. VBIBraPil164347_1563.

Phylogenomic databases

HOGENOMiHOG000096068.
KOiK00857.
OMAiIYSKRIV.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD8IEK0_BRAP9
AccessioniPrimary (citable) accession number: D8IEK0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: March 15, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.