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Protein

Elongation factor Tu

Gene

tuf

Organism
Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi88 – 92GTPUniRule annotation5
Nucleotide bindingi143 – 146GTPUniRule annotation4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:BP951000_1028Imported
OrganismiBrachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)Imported
Taxonomic identifieri759914 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesBrachyspiralesBrachyspiraceaeBrachyspira
Proteomesi
  • UP000000332 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi759914.BP951000_1028.

Structurei

3D structure databases

ProteinModelPortaliD8ICZ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 219Tr-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST210

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIEMFHKE.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8ICZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGTYEGTK THVNVGTIGH VDHGKTTLTS AITAVSSAMF PATVQKVAYD
60 70 80 90 100
SVAKASESQG RRDPTKILTI ATSHVEYESD NRHYAHVDCP GHADYIKNMI
110 120 130 140 150
TGAAQMDGAI LVVSAEDGVM PQTKEHVLLS RQVGVNYIVV FLNKCDKLDD
160 170 180 190 200
PEMAEIVEAE VVDVLDHYGF DGSKTPIIRG SAIKAIQAIE AGKDPRTDPD
210 220 230 240 250
CKCILDLLNA LDTYIPDPVR ETDKDFLMSI EDVYSIPGRG TVVTGRIERG
260 270 280 290 300
QIKKGDEVEI VGLRETKKTT CTGVEMFKKE VVGIAGYNVG CLLRGIERKE
310 320 330 340 350
VERGQVLAKP GTITPHKKFE AEVYILKKEE GGRHSGFVSG YRPQMYFRTT
360 370 380 390 400
DVTGVINLPE GSPMIMPGDN ANLTIELISQ IAMEEKQRFA IREGGKTVGN

GVVTKILE
Length:408
Mass (Da):44,512
Last modified:October 5, 2010 - v1
Checksum:iD615C1A8D89D08FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002025 Genomic DNA. Translation: ADK31019.1.
RefSeqiWP_013243972.1. NC_014330.1.

Genome annotation databases

EnsemblBacteriaiADK31019; ADK31019; BP951000_1028.
KEGGibpo:BP951000_1028.
PATRICi42196487. VBIBraPil164347_1006.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002025 Genomic DNA. Translation: ADK31019.1.
RefSeqiWP_013243972.1. NC_014330.1.

3D structure databases

ProteinModelPortaliD8ICZ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi759914.BP951000_1028.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADK31019; ADK31019; BP951000_1028.
KEGGibpo:BP951000_1028.
PATRICi42196487. VBIBraPil164347_1006.

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIEMFHKE.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD8ICZ6_BRAP9
AccessioniPrimary (citable) accession number: D8ICZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: November 2, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.