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D8IB51 (D8IB51_BRAP9) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:idh EMBL ADK30374.1
Ordered Locus Names:BP951000_0369
OrganismBrachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000) [Complete proteome] [HAMAP]
Taxonomic identifier759914 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Brachyspiraceae › Brachyspira ›

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
D8IB51 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 7ECD11E459E267E3

FASTA41946,201
        10         20         30         40         50         60 
MSKIEMKNGK LIVPNKVTIP FIEGDGVGAE ITPASQMVVN AAVKKAYNGE KSIEWLEVLA 

        70         80         90        100        110        120 
GDKAQKELGT PLPDETINTF KEYLIGIKGP LTTPVGEGMR SLNVALRQTL DLYVCLRPVR 

       130        140        150        160        170        180 
WFKGTSSPIK EPNKVNMVVF RENTEDIYAG IEWKTGTEEA KKFYNFLKNE MGVTKVRFPE 

       190        200        210        220        230        240 
TSSFGVKPVS EEGSKRLIRS AIEYALLNKL PSVTLVHKGN IMKFTEGGFK KYGYELARKE 

       250        260        270        280        290        300 
FAHQTFTMEE YAEIKKEFGE DKAKEKLKEA KEQGKLIIKD NICDAFLQNT LLKPEDYSVI 

       310        320        330        340        350        360 
ATLNLNGDYI SDQLAAMVGG IGIAPGGNIN YKTGHAIFEA THGTAPDIAG KNKANPCSLI 

       370        380        390        400        410 
LSSVMALEYL NMNEAASLII NALEKSFESG YATEDLASFM DNGTVLGTKE FAEKIVSIM

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References

[1]"The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes."
Wanchanthuek P., Bellgard M.I., La T., Ryan K., Moolhuijzen P., Chapman B., Black M., Schibeci D., Hunter A., Barrero R., Phillips N.D., Hampson D.J.
PLoS ONE 5:E11455-E11455(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1826 / 95/1000.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002025 Genomic DNA. Translation: ADK30374.1.
RefSeqYP_003784875.1. NC_014330.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADK30374; ADK30374; BP951000_0369.
GeneID9450488.
KEGGbpo:BP951000_0369.
PATRIC42195177. VBIBraPil164347_0363.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.

Enzyme and pathway databases

BioCycBPIL759914:GHZ5-369-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD8IB51_BRAP9
AccessionPrimary (citable) accession number: D8IB51
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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