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Protein

RNA polymerase sigma factor

Gene

rpoE

Organism
Amycolatopsis mediterranei (strain U-32)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factorUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAMED749927:GCZN-3602-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Name:rpoEImported
Ordered Locus Names:AMED_3616Imported
OrganismiAmycolatopsis mediterranei (strain U-32)Imported
Taxonomic identifieri749927 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
ProteomesiUP000000328 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the sigma-70 factor family. ECF subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000220479.
KOiK03088.
OMAiMTETENG.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009959. Cyclase_SnoaL-like_dom.
IPR014284. RNA_pol_sigma-70_dom.
IPR014305. RNA_pol_sigma-G_actinobac.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
PF12680. SnoaL_2. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02937. sigma70-ECF. 1 hit.
TIGR02960. SigX5. 1 hit.
PROSITEiPS01063. SIGMA70_ECF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8I8R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTETENGNED FGRLSEPFRR ELLAYCYRVL GSIDEAEEVV QDVYLDAWRA
60 70 80 90 100
YGGFEGRSSL RTWLYRIATR ACFKALEKSR RRPLPADLGA PEARPEARLV
110 120 130 140 150
EPTSEVPWLQ PAPDLLFATT PADPATVVVQ RHTMRLALIG ALQQLPPRQR
160 170 180 190 200
AVLILRDVLQ WRTAEVAELL EMTTAAVNSA LQRARAQVPL EEDDLTEPAE
210 220 230 240 250
PRQRALLDRY VTAFETADVD QLVAVLTQDA RWEMPPISTW FEGRDTILAF
260 270 280 290 300
LARQMPIIGP AELVATAANG QPAFAVYARG HDGARRPHAL HVLTMTAEGV
310
SRIVAFHGSA LFPLFGL
Length:317
Mass (Da):35,363
Last modified:October 5, 2010 - v1
Checksum:i8F7AEAD7102713B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002000 Genomic DNA. Translation: ADJ45399.1.
RefSeqiYP_003765801.1. NC_014318.1.

Genome annotation databases

EnsemblBacteriaiADJ45399; ADJ45399; AMED_3616.
GeneIDi9437811.
KEGGiamd:AMED_3616.
PATRICi42154376. VBIAmyMed151214_3735.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002000 Genomic DNA. Translation: ADJ45399.1.
RefSeqiYP_003765801.1. NC_014318.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADJ45399; ADJ45399; AMED_3616.
GeneIDi9437811.
KEGGiamd:AMED_3616.
PATRICi42154376. VBIAmyMed151214_3735.

Phylogenomic databases

HOGENOMiHOG000220479.
KOiK03088.
OMAiMTETENG.

Enzyme and pathway databases

BioCyciAMED749927:GCZN-3602-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009959. Cyclase_SnoaL-like_dom.
IPR014284. RNA_pol_sigma-70_dom.
IPR014305. RNA_pol_sigma-G_actinobac.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
PF12680. SnoaL_2. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02937. sigma70-ECF. 1 hit.
TIGR02960. SigX5. 1 hit.
PROSITEiPS01063. SIGMA70_ECF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism."
    Zhao W., Zhong Y., Yuan H., Wang J., Zheng H., Wang Y., Cen X., Xu F., Bai J., Han X., Lu G., Zhu Y., Shao Z., Yan H., Li C., Peng N., Zhang Z., Zhang Y.
    , Lin W., Fan Y., Qin Z., Hu Y., Zhu B., Wang S., Ding X., Zhao G.P.
    Cell Res. 20:1096-1108(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U-32Imported.

Entry informationi

Entry nameiD8I8R1_AMYMU
AccessioniPrimary (citable) accession number: D8I8R1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: March 4, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.