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Protein
Submitted name:

ATP-dependent DNA ligase

Gene

lig

Organism
Amycolatopsis mediterranei (strain U-32)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciAMED749927:GCZN-4128-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligaseImported
Gene namesi
Name:ligImported
Ordered Locus Names:AMED_4148Imported
OrganismiAmycolatopsis mediterranei (strain U-32)Imported
Taxonomic identifieri749927 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
ProteomesiUP000000328: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD8HR23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000222508.
KOiK01971.
OMAiHERTADC.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8HR23-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPPVRPMLAK AVHEVPRDPG LLYEPKWDGF RCVVFRDGDE IELGSRNDRP
60 70 80 90 100
LTRYFPELVE LLAAALPPRC VVDGEIVLVT PAGLDFEVLQ LRLHPAASRV
110 120 130 140 150
RKLAEETPAS FIAFDLLALG DTDLTEEPFR ERRKQLESVL STAAEGLQRV
160 170 180 190 200
HLTPLSDDPA QAEDWFTRFE GAGFDGVMAK PGDLPYEQDK RVMLKVKHER
210 220 230 240 250
TADCVVTGFR WHKDGAGVGS LLLGLFDDEG VLHHVGVASS FTKARRAELV
260 270 280 290 300
DELAPLRENA LEGHPWRNWA EYEPQPGRQP GANSRWAPQK DLSWEPLRPE
310 320 330 340 350
WVAEVRYEHL QGGRFRHGGR LVRFRPDRTP ESCTYAQLDE APPAELAKLL

GEAR
Length:354
Mass (Da):39,853
Last modified:October 5, 2010 - v1
Checksum:i836C1C906AD7ED23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002000 Genomic DNA. Translation: ADJ45925.1.
RefSeqiYP_003766327.1. NC_014318.1.

Genome annotation databases

EnsemblBacteriaiADJ45925; ADJ45925; AMED_4148.
GeneIDi9438337.
KEGGiamd:AMED_4148.
PATRICi42155487. VBIAmyMed151214_4290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002000 Genomic DNA. Translation: ADJ45925.1.
RefSeqiYP_003766327.1. NC_014318.1.

3D structure databases

ProteinModelPortaliD8HR23.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADJ45925; ADJ45925; AMED_4148.
GeneIDi9438337.
KEGGiamd:AMED_4148.
PATRICi42155487. VBIAmyMed151214_4290.

Phylogenomic databases

HOGENOMiHOG000222508.
KOiK01971.
OMAiHERTADC.

Enzyme and pathway databases

BioCyciAMED749927:GCZN-4128-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism."
    Zhao W., Zhong Y., Yuan H., Wang J., Zheng H., Wang Y., Cen X., Xu F., Bai J., Han X., Lu G., Zhu Y., Shao Z., Yan H., Li C., Peng N., Zhang Z., Zhang Y.
    , Lin W., Fan Y., Qin Z., Hu Y., Zhu B., Wang S., Ding X., Zhao G.P.
    Cell Res. 20:1096-1108(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U-32Imported.

Entry informationi

Entry nameiD8HR23_AMYMU
AccessioniPrimary (citable) accession number: D8HR23
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: January 7, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.