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D8HLT9 (D8HLT9_AMYMU) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617
Gene names
Name:lig EMBL ADJ49767.1
Ordered Locus Names:AMED_8064
OrganismAmycolatopsis mediterranei (strain U-32) [Complete proteome] [HAMAP] EMBL ADJ49767.1
Taxonomic identifier749927 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Amycolatopsis ›

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Sequences

Sequence LengthMass (Da)Tools
D8HLT9 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 1A349D55022D5068

FASTA51054,598
        10         20         30         40         50         60 
MLLSELVRAS AELAATRSRK AKIALLAELL RAAEIAELPT VIAYLTGQTA QDRLGAGWRT 

        70         80         90        100        110        120 
LAALGAGAAA GPVASVLEVD AALTAAAGVA AGTGSSTRRQ EVLRALFERL TKDEQQFLFR 

       130        140        150        160        170        180 
LVTGELRQGA LEGVMVDAIA AAAEVPAEDV RRAFMLSGKL GVTGVAAMTG GQAALAEFRL 

       190        200        210        220        230        240 
TLGTPIKPML ASPAESLDEA VAEHAEAIVE YKMDGARIQV HRQGDEVHVW TRTLREITGS 

       250        260        270        280        290        300 
VQELVDLVRA LPCESVVLDG ETLALTDAGR PRPFQDTMSR FGSTREEQVK ALLLRPYFFD 

       310        320        330        340        350        360 
CLHLDGVDLL DAPLSERNAA LRKVAGAHVI PGEVGTAGAA AVLEAAMEAG HEGVMVKDLA 

       370        380        390        400        410        420 
APYAAGRRGR AWLKVKPVHT IDLVVLAAEW GHGRRTGTLS NLHLGARDPD GGPPIMVGKT 

       430        440        450        460        470        480 
FKGMTDELLA WQTRTFQEIE THRDEWTVYV RPEVVVEIEL DSAQVSTRYP GGLALRFARV 

       490        500        510 
VRYRPDKDPA DADTIDTVRG LLHGDRSEGS

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References

[1]"Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism."
Zhao W., Zhong Y., Yuan H., Wang J., Zheng H., Wang Y., Cen X., Xu F., Bai J., Han X., Lu G., Zhu Y., Shao Z., Yan H., Li C., Peng N., Zhang Z., Zhang Y. expand/collapse author list , Lin W., Fan Y., Qin Z., Hu Y., Zhu B., Wang S., Ding X., Zhao G.P.
Cell Res. 20:1096-1108(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: U-32.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002000 Genomic DNA. Translation: ADJ49767.1.
RefSeqYP_003770169.1. NC_014318.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADJ49767; ADJ49767; AMED_8064.
GeneID9442203.
KEGGamd:AMED_8064.
PATRIC42163709. VBIAmyMed151214_8380.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK01971.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF117018. SSF117018. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD8HLT9_AMYMU
AccessionPrimary (citable) accession number: D8HLT9
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info