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D8H5I3 (D8H5I3_BACAI) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] synthase 2 PIRNR PIRNR000447
EC=2.3.1.179 PIRNR PIRNR000447
Gene names
Name:fabF EMBL ADK03891.1
Ordered Locus Names:BACI_c12110 EMBL ADK03891.1
OrganismBacillus cereus var. anthracis (strain CI) [Complete proteome] [HAMAP] EMBL ADK03891.1
Taxonomic identifier637380 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group ›

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP By similarity. PIRNR PIRNR000447

Catalytic activity

(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]. PIRNR PIRNR000447

Pathway

Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000447

Sequence similarities

Belongs to the beta-ketoacyl-ACP synthases family. PIRNR PIRNR000447 RuleBase RU003694

Sequences

Sequence LengthMass (Da)Tools
D8H5I3 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 4FFF2BACDADE6BAE

FASTA41243,702
        10         20         30         40         50         60 
MEKKRVVITG LGAVTPVGTD VETAWENIKK GVSGIGRLTR IDPELFPAKV AAEINDFEVE 

        70         80         90        100        110        120 
KYIDKKEARR MDRFTQYAVA AAKMAVADAK LEITEENGPR IGVWIGSGIG GMETYEEQFK 

       130        140        150        160        170        180 
IFTEKGPRRV SPFFVPMMIP DMAAGQVSIA TGAKGINTCS VTACASGANS IGDAFKAIQR 

       190        200        210        220        230        240 
GDADAMITGG AEAPLTSMAF AGFSSAKALT FNEDPATACR PFDKNRSGFV MGEGSGILIL 

       250        260        270        280        290        300 
EELEHALARG AHIYAEIAGY GATGDAFHIT MPAPGGEGGV RAMRQALADA GLQPEDIDYI 

       310        320        330        340        350        360 
NAHGTSTDAN EKYETMAIKE TFGEHAYKVA ISSTKSMTGH LLGAAGAVEA IFSIKSITDG 

       370        380        390        400        410 
VIPPTINYET PDPECDLDYV PNNARHQEVN AVLSNSLGFG GHNAVLVFKS YK

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References

[1]"The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids."
Klee S.R., Brzuszkiewicz E.B., Nattermann H., Bruggemann H., Dupke S., Wollherr A., Franz T., Pauli G., Appel B., Liebl W., Couacy-Hymann E., Boesch C., Meyer F.D., Leendertz F.H., Ellerbrok H., Gottschalk G., Grunow R., Liesegang H.
PLoS ONE 5:E10986-E10986(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CI EMBL ADK03891.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001746 Genomic DNA. Translation: ADK03891.1.
RefSeqYP_003791029.1. NC_014335.1.

3D structure databases

ProteinModelPortalD8H5I3.
SMRD8H5I3. Positions 4-412.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADK03891; ADK03891; BACI_c12110.
GeneID9453718.
KEGGbal:BACI_c12110.
PATRIC42177025. VBIBacCer111781_1470.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000060166.
KOK09458.

Enzyme and pathway databases

BioCycBCER637380:GHO7-1186-MONOMER.
UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR017568. 3-oxoacyl-ACP_synth-2.
IPR014031. Ketoacyl_synth_C.
IPR014030. Ketoacyl_synth_N.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF00109. ketoacyl-synt. 1 hit.
PF02801. Ketoacyl-synt_C. 1 hit.
[Graphical view]
PIRSFPIRSF000447. KAS_II. 1 hit.
SUPFAMSSF53901. Thiolase-like. 2 hits.
TIGRFAMsTIGR03150. fabF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD8H5I3_BACAI
AccessionPrimary (citable) accession number: D8H5I3
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info