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D8GXH2

- D8GXH2_BACAI

UniProt

D8GXH2 - D8GXH2_BACAI

Protein

Elongation factor Tu

Gene

tuf

Organism
Bacillus cereus var. anthracis (strain CI)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBCER637380:GHO7-132-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:BACI_c01350Imported
    OrganismiBacillus cereus var. anthracis (strain CI)Imported
    Taxonomic identifieri637380 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000001657: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiD8GXH2.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD8GXH2.
    SMRiD8GXH2. Positions 2-394.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D8GXH2-1 [UniParc]FASTAAdd to Basket

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    MAKAKFERSK PHVNIGTIGH VDHGKTTLTA AITTVLAKAG GAEARGYDQI    50
    DAAPEERERG ITISTAHVEY ETETRHYAHV DCPGHADYVK NMITGAAQMD 100
    GGILVVSAAD GPMPQTREHI LLSRQVGVPY IVVFLNKCDM VDDEELLELV 150
    EMEVRDLLSE YGFPGDDIPV IKGSALKALQ GEADWEAKII ELMAEVDAYI 200
    PTPERETDKP FLMPVEDVFS ITGRGTVATG RVERGIVKVG DVVEIIGLAE 250
    ENASTTVTGV EMFRKLLDQA QAGDNIGALL RGVAREDIQR GQVLAKSGSV 300
    KAHAKFKAEV FVLSKEEGGR HTPFFANYRP QFYFRTTDVT GIIQLPEGTE 350
    MVMPGDNIEM TIELIAPIAI EEGTKFSIRE GGRTVGYGVV ATIVE 395
    Length:395
    Mass (Da):42,939
    Last modified:October 5, 2010 - v1
    Checksum:i6B84CB113167D4FD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001746 Genomic DNA. Translation: ADK02918.1.
    RefSeqiYP_003790056.1. NC_014335.1.

    Genome annotation databases

    EnsemblBacteriaiADK02918; ADK02918; BACI_c01350.
    GeneIDi9452664.
    KEGGibal:BACI_c01350.
    PATRICi42174805. VBIBacCer111781_0429.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001746 Genomic DNA. Translation: ADK02918.1 .
    RefSeqi YP_003790056.1. NC_014335.1.

    3D structure databases

    ProteinModelPortali D8GXH2.
    SMRi D8GXH2. Positions 2-394.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D8GXH2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADK02918 ; ADK02918 ; BACI_c01350 .
    GeneIDi 9452664.
    KEGGi bal:BACI_c01350.
    PATRICi 42174805. VBIBacCer111781_0429.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci BCER637380:GHO7-132-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids."
      Klee S.R., Brzuszkiewicz E.B., Nattermann H., Bruggemann H., Dupke S., Wollherr A., Franz T., Pauli G., Appel B., Liebl W., Couacy-Hymann E., Boesch C., Meyer F.D., Leendertz F.H., Ellerbrok H., Gottschalk G., Grunow R., Liesegang H.
      PLoS ONE 5:E10986-E10986(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CIImported.

    Entry informationi

    Entry nameiD8GXH2_BACAI
    AccessioniPrimary (citable) accession number: D8GXH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3