D8GU52 (D8GU52_CLOLD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional aldehyde/alcohol dehydrogenase EMBL ADK14715.1
EC=1.1.1.1 EMBL ADK14715.1
EC=1.2.1.10 EMBL ADK14715.1

Gene names

Name:	adhE1 EMBL ADK14715.1
Ordered Locus Names:	CLJU_c16510 EMBL ADK14715.1

Organism

Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC) [Complete proteome] [HAMAP]

Taxonomic identifier

748727 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium ljungdahlii

Protein attributes

Sequence length	870 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ADK14715.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	alcohol metabolic process Inferred from electronic annotation. Source: InterPro carbon utilization Inferred from electronic annotation. Source: InterPro
Molecular_function	acetaldehyde dehydrogenase (acetylating) activity Inferred from electronic annotation. Source: EC alcohol dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D8GU52 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: 25F4999DEA6A5A5E	FASTA	870	95,020
	10 20 30 40 50 60 MKVTNVEELM KRLEEIKDAQ KKFATYTQEQ VDEIFRQAAM AANSARIELA KMAVEESGMG 70 80 90 100 110 120 IVEDKVIKNH FASEYIYNKY KDEKTCGVLE RDAGFGIVRI AEPVGVIAAV VPTTNPTSTA 130 140 150 160 170 180 IFKSLIALKT RNGIIFSPHP RAKKSTIAAA KIVLDAAVKA GAPEGIIGWI DEPSIELSQV 190 200 210 220 230 240 VMGEANLILA TGGPGMVKAA YSSGKPAVGV GPGNTPAVID ESADIKMAVN SILLSKTFDN 250 260 270 280 290 300 GMICASEQSV IVLDSIYEEV KKEFAYRGAY ILSKDETDKV GKIILKNGAL NAGIVGQPAF 310 320 330 340 350 360 KIAQLAGVDV PEKAKVLIGE VESVELEEPF SHEKLSPVLA MYRARNFEDA IAKTDKLVRS 370 380 390 400 410 420 GGFGHTSSLY VNPMTEKAKV EKFSTMMKTS RTIINTPSSQ GGIGDIYNFK LAPSLTLGCG 430 440 450 460 470 480 SWGGNSVSEN VGPKHLLNIK SVAERRENML WFRVPEKVYF KYGSLGVALK ELKVMNKKKV 490 500 510 520 530 540 FIVTDKVLYQ LGYVDKVTKV LEELKISYKV FTDVEPDPTL ATAKKGAAEL LSYEPDTIIS 550 560 570 580 590 600 VGGGSAMDAA KIMWVMYEHP EVKFEDLAMR FMDIRKRVYV FPKMGEKAMM ISVATSAGTG 610 620 630 640 650 660 SEVTPFAVIT DEKTGAKYPL ADYELTPDMA IVDAELMMGM PRGLTAASGI DALTHALEAY 670 680 690 700 710 720 VSIMATEFTN GLALEAVKLI FEYLPKAYTE GTTNVKAREK MVHASCIAGM AFANAFLGVC 730 740 750 760 770 780 HSMAHKLGAQ HHIPHGIANA LMIDEVIKFN AVDDPIKQAA FPQYEYPNAR YRYAQIADCL 790 800 810 820 830 840 NLGGNTEEEK VQLLINAIDD LKAKLNIPET IKEAGVSEDK FYATLDKMSE LAFDDQCTGA 850 860 870 NPRYPLISEI KQMYINVFDK TEPIVEDEEK

References

[1]

"Clostridium ljungdahlii represents a microbial production platform based on syngas." Kopke M., Held C., Hujer S., Liesegang H., Wiezer A., Wollherr A., Ehrenreich A., Liebl W., Gottschalk G., Durre P. Proc. Natl. Acad. Sci. U.S.A. 107:13087-13092(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 55383 / DSM 13528 / PETC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001666 Genomic DNA. Translation: ADK14715.1.
RefSeq	YP_003779817.1. NC_014328.1.
3D structure databases
ProteinModelPortal	D8GU52.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADK14715; ADK14715; CLJU_c16510.
GeneID	9445268.
KEGG	clj:CLJU_c16510.
PATRIC	42484522. VBICloLju82977_1628.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000025256.
KO	K04072.
Enzyme and pathway databases
BioCyc	CLJU748727:GHMO-1651-MONOMER.
Family and domain databases
Gene3D	3.40.309.10. 2 hits. 3.40.605.10. 1 hit.
InterPro	IPR001670. ADH_Fe. IPR018211. ADH_Fe_CS. IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR012079. Bifunc_Ald/ADH. [Graphical view]
Pfam	PF00171. Aldedh. 1 hit. PF00465. Fe-ADH. 1 hit. [Graphical view]
PIRSF	PIRSF000111. ALDH_ADH. 1 hit.
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00913. ADH_IRON_1. 1 hit. PS00060. ADH_IRON_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D8GU52_CLOLD

Accession

Primary (citable) accession number: D8GU52

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)