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Protein

Thioredoxin reductase

Gene

CLJU_c27810

Organism
Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thioredoxin + NADP+ = thioredoxin disulfide + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
LigandFADUniRule annotation, Flavoprotein, NADPUniRule annotation

Enzyme and pathway databases

BioCyciCLJU748727:G1GM0-2769-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin reductaseUniRule annotation (EC:1.8.1.9UniRule annotation)
Gene namesi
Ordered Locus Names:CLJU_c27810Imported
OrganismiClostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)Imported
Taxonomic identifieri748727 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001656 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi748727.CLJU_c27810

Structurei

3D structure databases

ProteinModelPortaliD8GNH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3M Bacteria
COG0492 LUCA
HOGENOMiHOG000072911
KOiK00384
OMAiIVELAMP
OrthoDBiPOG091H02HU

Family and domain databases

Gene3Di3.50.50.603 hits
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR008255 Pyr_nucl-diS_OxRdtase_2_AS
IPR000103 Pyridine_nuc-diS_OxRdtase_2
IPR005982 Thioredox_Rdtase
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
PRINTSiPR00469 PNDRDTASEII
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01292 TRX_reduct, 1 hit
PROSITEiView protein in PROSITE
PS00573 PYRIDINE_REDOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

D8GNH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNIYDVIII GSGPAGLSAA LYSARAKMKT LLLERSKAGG QIVITDEVAN
60 70 80 90 100
YPGSIKEATG PSLIARMEEQ VESFGAERKK DEIKEVDFTG KIKRLKGIKE
110 120 130 140 150
EYQAKAVIIA TGATPRHIGC PGENQLIGKG VSYCATCDAE FFEDLEVFVV
160 170 180 190 200
GGGDAAIEEA LYLTKFAKKV TIVHRRDELR AAKSIQEKAF KNPKVEIMWN
210 220 230 240 250
KVITELKGDG LLESAVFKDT KTGEINEYFA DEEDGTFGVF VFVGYLPING
260 270 280 290 300
LFKDKITMNK AGYIITNDKM ETNISGVFAA GDIREKPLRQ VVTAAADGAI
310
AAVEAGKYIE NNFEE
Length:315
Mass (Da):34,355
Last modified:October 5, 2010 - v1
Checksum:i89C718C33D247181
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001666 Genomic DNA Translation: ADK15835.1
RefSeqiWP_013239425.1, NZ_LITS01000025.1

Genome annotation databases

EnsemblBacteriaiADK15835; ADK15835; CLJU_c27810
KEGGiclj:CLJU_c27810
PATRICifig|748727.19.peg.1768

Similar proteinsi

Entry informationi

Entry nameiD8GNH2_CLOLD
AccessioniPrimary (citable) accession number: D8GNH2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 25, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported