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Protein

Elongation factor Tu

Gene

tuf1

Organism
Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCLJU748727:GHMO-4105-MONOMER.
CLJU748727:GHMO-4119-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1Imported
Synonyms:tufUniRule annotation, tuf2Imported
Ordered Locus Names:CLJU_c41060Imported, CLJU_c41200Imported
OrganismiClostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)Imported
Taxonomic identifieri748727 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001656 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi748727.CLJU_c41200.

Structurei

3D structure databases

ProteinModelPortaliD8GJ42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiDYGEIDK.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8GJ42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKEKYERTK PHVNIGTIGH VDHGKTTLTA AITMVLSKEG KAAATKYDEI
60 70 80 90 100
DKAPEEKERG ITINTAHVEY ETDKRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHI LLASRVGVQY IVVFLNKSDQ VDDPELLELV
160 170 180 190 200
EMEVRELLSE YGFPGDDVPI IVGSALKVLE NPDDPETTKC IHELMDAVDE
210 220 230 240 250
YIPTPERPTD KDFLMPIEDV FTITGRGTVA TGRVESGVLK IGDELEIVGL
260 270 280 290 300
KEEKKKTTCT GVEMFRKLLD QAMAGDNIGV LLRGIQRDEV ERGQVLAKPG
310 320 330 340 350
TVHPHKKFVG QVYVLKKEEG GRHTPFFNGY RPQFYFRTTD VTGSIALPEG
360 370 380 390
VEMVMPGDHI DMNVELITPV AMHEGLRFAI REGGRTVGSG VVTTITE
Length:397
Mass (Da):43,791
Last modified:October 5, 2010 - v1
Checksum:iD3E4795EB815DA8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001666 Genomic DNA. Translation: ADK17130.1.
CP001666 Genomic DNA. Translation: ADK17144.1.
RefSeqiWP_013240693.1. NC_014328.1.
YP_003782232.1. NC_014328.1.
YP_003782246.1. NC_014328.1.

Genome annotation databases

EnsemblBacteriaiADK17130; ADK17130; CLJU_c41060.
ADK17144; ADK17144; CLJU_c41200.
KEGGiclj:CLJU_c41060.
clj:CLJU_c41200.
PATRICi42489653. VBICloLju82977_4165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001666 Genomic DNA. Translation: ADK17130.1.
CP001666 Genomic DNA. Translation: ADK17144.1.
RefSeqiWP_013240693.1. NC_014328.1.
YP_003782232.1. NC_014328.1.
YP_003782246.1. NC_014328.1.

3D structure databases

ProteinModelPortaliD8GJ42.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi748727.CLJU_c41200.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADK17130; ADK17130; CLJU_c41060.
ADK17144; ADK17144; CLJU_c41200.
KEGGiclj:CLJU_c41060.
clj:CLJU_c41200.
PATRICi42489653. VBICloLju82977_4165.

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiDYGEIDK.

Enzyme and pathway databases

BioCyciCLJU748727:GHMO-4105-MONOMER.
CLJU748727:GHMO-4119-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Koepke M., Hujer S., Held C., Wiezer A., Liesegang H., Ehrenreich A., Gottschalk G., Duerre P.
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 13528Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55383 / DSM 13528 / PETCImported and DSM 13528Imported.

Entry informationi

Entry nameiD8GJ42_CLOLD
AccessioniPrimary (citable) accession number: D8GJ42
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.