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D8GI25

- D8GI25_CLOLD

UniProt

D8GI25 - D8GI25_CLOLD

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Protein

Xylose isomerase

Gene

xylA

Organism
Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011UniRule annotation
Active sitei104 – 1041UniRule annotation
Metal bindingi232 – 2321Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 2UniRule annotation
Metal bindingi271 – 2711Magnesium 2UniRule annotation
Metal bindingi296 – 2961Magnesium 1UniRule annotation
Metal bindingi307 – 3071Magnesium 2UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCLJU748727:GHMO-1824-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:CLJU_c18240Imported
OrganismiClostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)Imported
Taxonomic identifieri748727 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001656: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD8GI25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293.
KOiK01805.
OMAiCMDATHK.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8GI25 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKEYFNNVSK INYEGPDSKN PYSFKYYNPD EVIGGKKMRD HLRFSMSYWH
60 70 80 90 100
TLTANGTDQF GSGTMVRPWD NVNDKMELAK ARMEAAFEFM NKLDIDYFCF
110 120 130 140 150
HDRDIAPEGK DLAETNKNLD EIVAMCKDLM KKNNKKLLWG TANLFNNPRF
160 170 180 190 200
VHGAGTTCNA NVYAYSAAQL KKAIEVTNEL GGENYVFWGG REGYETLLNT
210 220 230 240 250
DMGFEMDNFA RILQMAVDYA KKIGFKGQFL IEPKPKEPTK HQYDFDVATV
260 270 280 290 300
LGFLRKYKLE DYFKINIEAN HATLAGHTFQ HEICLARNNN ALGSLDANQG
310 320 330 340 350
DPHLGWDTDQ FPTNVYDTTL SMYEVLKNGG IAPGGLNFDA KVRRASFEPE
360 370 380 390 400
DLFLAYIAGM DSFAKGLRVA YKLLQDAPIE NFIKERYSSF STGIGKDIVD
410 420 430 440
GKVGFDELEK YALENNVINN KSGRQEYLES VVNQYILEDK
Length:440
Mass (Da):50,112
Last modified:October 5, 2010 - v1
Checksum:iA76171A640A04875
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001666 Genomic DNA. Translation: ADK14887.1.
RefSeqiYP_003779989.1. NC_014328.1.

Genome annotation databases

EnsemblBacteriaiADK14887; ADK14887; CLJU_c18240.
GeneIDi9445441.
KEGGiclj:CLJU_c18240.
PATRICi42484881. VBICloLju82977_1807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001666 Genomic DNA. Translation: ADK14887.1 .
RefSeqi YP_003779989.1. NC_014328.1.

3D structure databases

ProteinModelPortali D8GI25.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADK14887 ; ADK14887 ; CLJU_c18240 .
GeneIDi 9445441.
KEGGi clj:CLJU_c18240.
PATRICi 42484881. VBICloLju82977_1807.

Phylogenomic databases

HOGENOMi HOG000252293.
KOi K01805.
OMAi CMDATHK.

Enzyme and pathway databases

BioCyci CLJU748727:GHMO-1824-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55383 / DSM 13528 / PETCImported.

Entry informationi

Entry nameiD8GI25_CLOLD
AccessioniPrimary (citable) accession number: D8GI25
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3