D8GCQ2 (D8GCQ2_LACCZ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

LCAZH_2523 EMBL ADK19714.1

Organism

Lactobacillus casei (strain Zhang) [Complete proteome] [HAMAP] EMBL ADK19714.1

Taxonomic identifier

498216 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus casei group › Lactobacillus casei

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D8GCQ2 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: 3D6D3A712D7A5CAD	FASTA	378	41,332
	10 20 30 40 50 60 MTIGNFRPAK VLIDETAILH NIQHEVARLK KQTQLFAVVK ADAYGHGMLR VARVAKAAGA 70 80 90 100 110 120 TGFCVAILDE ALGLRKADYS EPVLVLGIVP SQYAAIAAAQ TISLPVSSTE WLEQALPVLE 130 140 150 160 170 180 AQPELPPLRI HLALDTGMGR IGFTEDQALK TAVAFVEAHS KQFVIEGIFT HFATADAPDD 190 200 210 220 230 240 TYFKQQVDKF NHLVDLLPSR PRYVHVSNSA TSLWHAACNG NMIRYGVAIY GLNPSGDAIP 250 260 270 280 290 300 TTPFPLEPAL SLESELTYCK QVHAGDGISY GVTYRAKGDE FIGTVPIGYA DGWLRRLQGF 310 320 330 340 350 360 HVLVDGQYCE IVGRICMDQF MIRLPKAYPA GTKVVLVGQS GDQEITLLDV AKYSKTIHYE 370 IACNLTPRLK RQSVNPVD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Meng H. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Zhang.
[2]	"Complete genome sequence of Lactobacillus casei Zhang, a new probiotic strain isolated from traditional homemade koumiss in Inner Mongolia, China." Zhang W., Yu D., Sun Z., Wu R., Chen X., Chen W., Meng H., Hu S., Zhang H. J. Bacteriol. 192:5268-5269(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Zhang EMBL ADK19714.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001084 Genomic DNA. Translation: ADK19714.1.
RefSeq	YP_003789564.1. NC_014334.1.
3D structure databases
ProteinModelPortal	D8GCQ2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADK19714; ADK19714; LCAZH_2523.
GeneID	9460432.
KEGG	lcz:LCAZH_2523.
PATRIC	42380842. VBILacCas45142_2367.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
Enzyme and pathway databases
BioCyc	LCAS498216:GH2S-2512-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D8GCQ2_LACCZ

Accession

Primary (citable) accession number: D8GCQ2

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)