D8GC68 (D8GC68_LACCZ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
5-deoxy-glucuronate isomerase HAMAP-Rule MF_01673
Short name=5DG isomerase HAMAP-Rule MF_01673
EC=5.3.1.n1 HAMAP-Rule MF_01673

Gene names

Name:	iolB HAMAP-Rule MF_01673
Ordered Locus Names:	LCAZH_0253 EMBL ADK17549.1

Organism

Lactobacillus casei (strain Zhang) [Complete proteome] [HAMAP] EMBL ADK17549.1

Taxonomic identifier

498216 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus casei group › Lactobacillus casei

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate) By similarity. HAMAP-Rule MF_01673
Catalytic activity	5-deoxy-glucuronic acid = 5-dehydro-2-deoxy-D-gluconic acid. HAMAP-Rule MF_01673
Pathway	Polyol metabolism; myo-inositol degradation into acetyl-CoA; acetyl-CoA from myo-inositol: step 4/7. HAMAP-Rule MF_01673
Sequence similarities	Belongs to the isomerase IolB family. HAMAP-Rule MF_01673

Ontologies

Keywords
Molecular function	Isomerase SAAS SAAS021120 HAMAP-Rule MF_01673
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	glucuronate isomerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D8GC68 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: BBEBD02E695B8356	FASTA	271	30,842
	10 20 30 40 50 60 MSLLYHKQNQ ELSSGVRLIQ DVNASNSPMK YTAVKVLEFS ADSSYEETLE AFEAGIVVLE 70 80 90 100 110 120 GKVTITADDQ TFEDVGQRTS IFDKIPTDSV YVSTGLAFGI RAKQAAKILI AYAPTNQTFP 130 140 150 160 170 180 VRLIRGNIHQ VEHRGKYNNK RLVQNILPDN LPFADKLLLV EVYTDSANWS SYPPHRHDHD 190 200 210 220 230 240 DLPAESLLEE IYYHEMRPKQ GFVFQRVYTD DLSLDETMAV QNQDVVVVPK GYHPVGVPDG 250 260 270 YDSYYLNVMA GPTRVWHFHN APEHVWIIDR Q

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Meng H. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Zhang.
[2]	"Complete genome sequence of Lactobacillus casei Zhang, a new probiotic strain isolated from traditional homemade koumiss in Inner Mongolia, China." Zhang W., Yu D., Sun Z., Wu R., Chen X., Chen W., Meng H., Hu S., Zhang H. J. Bacteriol. 192:5268-5269(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Zhang EMBL ADK17549.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001084 Genomic DNA. Translation: ADK17549.1.
RefSeq	YP_003787399.1. NC_014334.1.
3D structure databases
ProteinModelPortal	D8GC68.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADK17549; ADK17549; LCAZH_0253.
GeneID	9458173.
KEGG	lcz:LCAZH_0253.
PATRIC	42376434. VBILacCas45142_0242.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000239754.
KO	K03337.
Enzyme and pathway databases
BioCyc	LCAS498216:GH2S-253-MONOMER.
UniPathway	UPA00076; UER00920.
Family and domain databases
Gene3D	2.60.120.10. 2 hits.
HAMAP	MF_01673. IolB.
InterPro	IPR024203. Deoxy-glucuronate_isom_IolB. IPR023770. IolB. IPR021120. KduI/IolB_isomerase. IPR014710. RmlC-like_jellyroll. IPR011051. RmlC_Cupin. [Graphical view]
Pfam	PF04962. KduI. 1 hit. [Graphical view]
PIRSF	PIRSF036628. IolB. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D8GC68_LACCZ

Accession

Primary (citable) accession number: D8GC68

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)