ID   D8F2H3_9DELT            Unreviewed;       507 AA.
AC   D8F2H3;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Toxin-antitoxin system, toxin component, Fic family {ECO:0000313|EMBL:EFK10026.1};
GN   ORFNames=NPH_1834 {ECO:0000313|EMBL:EFK10026.1};
OS   delta proteobacterium NaphS2.
OC   Bacteria; Deltaproteobacteria.
OX   NCBI_TaxID=88274 {ECO:0000313|EMBL:EFK10026.1, ECO:0000313|Proteomes:UP000003834};
RN   [1] {ECO:0000313|EMBL:EFK10026.1, ECO:0000313|Proteomes:UP000003834}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NaphS2 {ECO:0000313|EMBL:EFK10026.1,
RC   ECO:0000313|Proteomes:UP000003834};
RX   PubMed=21124915; DOI=10.1371/journal.pone.0014072;
RA   Didonato R.J., Young N.D., Butler J.E., Chin K.J., Hixson K.K., Mouser P.,
RA   Lipton M.S., Deboy R., Methe B.A.;
RT   "Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of
RT   Differential Gene Expression during Anaerobic Growth on Naphthalene.";
RL   PLoS ONE 5:E14072-E14072(2010).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFK10026.1}.
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DR   EMBL; ADZZ01000249; EFK10026.1; -; Genomic_DNA.
DR   AlphaFoldDB; D8F2H3; -.
DR   OrthoDB; 9813719at2; -.
DR   Proteomes; UP000003834; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3290.10; Fido-like domain; 1.
DR   InterPro; IPR003812; Fido.
DR   InterPro; IPR036597; Fido-like_dom_sf.
DR   InterPro; IPR040198; Fido_containing.
DR   PANTHER; PTHR13504; FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145; 1.
DR   PANTHER; PTHR13504:SF38; PROTEIN ADENYLYLTRANSFERASE AQ_AA38-RELATED; 1.
DR   Pfam; PF02661; Fic; 1.
DR   SUPFAM; SSF140931; Fic-like; 1.
DR   PROSITE; PS51459; FIDO; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003834}.
FT   DOMAIN          357..501
FT                   /note="Fido"
FT                   /evidence="ECO:0000259|PROSITE:PS51459"
FT   ACT_SITE        443
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-1"
FT   BINDING         447..454
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
SQ   SEQUENCE   507 AA;  57312 MW;  D0CAF7ED831FDD7B CRC64;
     MPTLQEKVAE SFAVLKKIQD EGIVAIQTKN MTRTHRERLV KSGFIKEVMK GWYISARPEE
     QTGESTAWYA SFWGFCGDYL NSRFGNQWCL SPEQSLRIHG ENWSVPNQLP VRTPTGGNKP
     ISLLHGTSIM DVRLNLPDRK DMEIKENIRI MTLPAALISC APAYYSNNTV EARAALSMIS
     DASGILHKLL EGGHSTVAGR LAGAFRNIGK NVIADDIIEA MRTAGYNITE NDPFEEKPVT
     ISSERELSPH VNRIRMYWAD MRGIVLENFP QAPLVRRNTD EYLKYVDEIY PADAYHSLSI
     EGYHVSELLI ERVRSGNWDP ETNRKDKAYA DALAARGYWQ AFQAVKKSLI KILNKNSPGT
     VVSNDHSIWY RELFAPSVSV GLMGASDLAG YRNQPVYIRK SRHVPPRCEA LRDLMPAFFS
     LLENEAEPAV NAVLGHFFFV YIHPYVDGNG RMGRFLMNVM LASGGYPWTV IPLETRKDYM
     AALEEASVRK NIVPFSRFLA ELVQKRQ
//