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Protein

Cysteine synthase

Gene

VIT_15s0046g02300

Organism
Vitis vinifera (Grape)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. cysteine synthase activity Source: UniProtKB-EC
  2. transferase activity Source: UniProtKB-KW

GO - Biological processi

  1. cysteine biosynthetic process from serine Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Cysteine biosynthesisUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine synthaseUniRule annotation (EC:2.5.1.47UniRule annotation)
Gene namesi
Ordered Locus Names:VIT_15s0046g02300Imported
OrganismiVitis vinifera (Grape)Imported
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis
ProteomesiUP000009183 Componenti: Chromosome 15

PTM / Processingi

Proteomic databases

PRIDEiD7UCD0.

Expressioni

Gene expression databases

ExpressionAtlasiD7UCD0. differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the cysteine synthase/cystathionine beta-synthase family.UniRule annotation

Phylogenomic databases

InParanoidiD7UCD0.
KOiK13034.
OMAiVKVHYET.

Family and domain databases

InterProiIPR005856. Cys_synthKM.
IPR005859. CysK.
IPR001216. P-phosphate_BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01139. cysK. 1 hit.
TIGR01136. cysKM. 1 hit.
PROSITEiPS00901. CYS_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7UCD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALSSFFKR KSSIPFTSLA IRRWFSTQPI LDSPSFSQRI RDLPKDLPGT
60 70 80 90 100
NIKKEVSQLI GKTPLVFLNK VTEGCGAYVA VKQEMMQPTA SIKDRPALAM
110 120 130 140 150
ITDAEDKQLI TPGKTVLIEP TSGNMGISMA FMAAMKGYKM VLTMPSYTSL
160 170 180 190 200
ERRVTMRAFG ADLILTDPTK GMGGTVKKAY ELLESTPDAF MLQQFSNPAN
210 220 230 240 250
TQVHFETTGP EIWEDTRGQV DIFIMGIGSG GTVSGVGRYL KSQNPNVKIY
260 270 280 290 300
GLEPTESNVL NGGKPGPHHI TGNGVGFKPD ILDMDVMEEV LMVSSEDAVN
310 320 330 340 350
MARQLALKEG LMVGISSGAN TVAALRLARR PENKGKLIVT IHPSFGERYL
360 370
SSVLFQELRK EAENMQPVSV D
Length:371
Mass (Da):40,499
Last modified:August 10, 2010 - v1
Checksum:iA6720F026D431916
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN596755 Genomic DNA. Translation: CBI40395.3.
RefSeqiXP_002276013.1. XM_002275977.3.
UniGeneiVvi.2604.

Genome annotation databases

EnsemblPlantsiVIT_15s0046g02300.t01; VIT_15s0046g02300.t01; VIT_15s0046g02300.
GeneIDi100255091.
KEGGivvi:100255091.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN596755 Genomic DNA. Translation: CBI40395.3.
RefSeqiXP_002276013.1. XM_002275977.3.
UniGeneiVvi.2604.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD7UCD0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiVIT_15s0046g02300.t01; VIT_15s0046g02300.t01; VIT_15s0046g02300.
GeneIDi100255091.
KEGGivvi:100255091.

Phylogenomic databases

InParanoidiD7UCD0.
KOiK13034.
OMAiVKVHYET.

Gene expression databases

ExpressionAtlasiD7UCD0. differential.

Family and domain databases

InterProiIPR005856. Cys_synthKM.
IPR005859. CysK.
IPR001216. P-phosphate_BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01139. cysK. 1 hit.
TIGR01136. cysKM. 1 hit.
PROSITEiPS00901. CYS_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla."
    The French-Italian Public Consortium for Grapevine Genome Characterization.
    Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A., Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F., Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.
    , Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E., Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M., Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M., Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E., Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M., Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G., Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F., Wincker P.
    Nature 449:463-467(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Pinot noir / PN40024Imported.

Entry informationi

Entry nameiD7UCD0_VITVI
AccessioniPrimary (citable) accession number: D7UCD0
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: March 4, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.