Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

VIT_04s0023g01650

Organism
Vitis vinifera (Grape)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (VIT_14s0219g00150), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (VIT_00s0304g00040), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (VITISV_023718), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (VIT_04s0023g01650)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
Ordered Locus Names:VIT_04s0023g01650Imported
OrganismiVitis vinifera (Grape)Imported
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis
Proteomesi
  • UP000009183 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

Expressioni

Gene expression databases

ExpressionAtlasiD7SPF1 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi29760.VIT_04s0023g01650.t01

Structurei

3D structure databases

ProteinModelPortaliD7SPF1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 483FAD_binding_2InterPro annotationAdd BLAST397
Domaini538 – 670Succ_DH_flav_CInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG2403 Eukaryota
COG1053 LUCA
HOGENOMiHOG000160475
InParanoidiD7SPF1
KOiK00234
OMAiGDSPWEH
OrthoDBiEOG093604YT

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

D7SPF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRCVSRGLR FRSSDSKRSL TSEYLKPHIS RFFSTESTGG GSSGTSEAEI
60 70 80 90 100
KAAIGELSKH GVDTAGITEL YRSSYTSSYT IVDHTYDAVV VGAGGAGLRA
110 120 130 140 150
AIGLSEHGFN TACITKLFPT RSHTVAAQGG INAALGNMTE DDWRWHMYDT
160 170 180 190 200
VKGSDWLGDQ DAIQYMCREA PKAVIELENY GLPFSRTEDG RIYQRAFGGQ
210 220 230 240 250
SLNFGKGGQA YRCACAADRT GHALLHTLYG QAMKHNTQFF VEYFALDLLM
260 270 280 290 300
DNDGACQGVI ALNMEDGTLH RFQAASTILA TGGYGRTYFS ATSAHTCTGD
310 320 330 340 350
GNAMVARAGL PLQDLEFVQF HPTGIYGAGC LITEGSRGEG GILRNSEGER
360 370 380 390 400
FMERYAPTAK DLASRDVVSR SMTMEIREGR GVGPLKDHIY LHLNHLPPEV
410 420 430 440 450
LKERLPGISE TAAIFAGVDV TKEPIPVLPT VHYNMGGIPT NYHGEVLTIK
460 470 480 490 500
GNDPDAVVPG LMAAGEAACA SVHGANRLGA NSLLDIVVFG RACANRVAEI
510 520 530 540 550
HKPGEKQKPL EKDSGEKTIA WLDKLRNSNG SIPTSKIRLN MQRVMQNNAA
560 570 580 590 600
VFRTQETLEE GCKLIDKAWE SFHDVQLKDR SLIWNSDLSE TIELENLLIN
610 620 630 640 650
ACITMHSAEA RKESRGAHAR EDFTKRDDEN WIRHTLGYWE NEKVRLDYRP
660 670
VHMNPLDDEI ESIPPKARVY
Length:670
Mass (Da):73,659
Last modified:August 10, 2010 - v1
Checksum:i8D6402C3882CA272
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN594959 Genomic DNA Translation: CBI17530.3
RefSeqiXP_002269407.1, XM_002269371.4
UniGeneiVvi.12221

Genome annotation databases

EnsemblPlantsiVIT_04s0023g01650.t01; VIT_04s0023g01650.t01; VIT_04s0023g01650
GeneIDi100254718
GrameneiVIT_04s0023g01650.t01; VIT_04s0023g01650.t01; VIT_04s0023g01650
KEGGivvi:100254718

Similar proteinsi

Entry informationi

Entry nameiD7SPF1_VITVI
AccessioniPrimary (citable) accession number: D7SPF1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health