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D7PBN4

- D7PBN4_HUMAN

UniProt

D7PBN4 - D7PBN4_HUMAN

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Protein
Submitted name: SLC45A3-BRAF fusion protein
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. MAP kinase kinase kinase activity Source: Ensembl

GO - Biological processi

  1. negative regulation of neuron apoptotic process Source: Ensembl
  2. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
  3. protein heterooligomerization Source: Ensembl
  4. response to cAMP Source: Ensembl
  5. response to epidermal growth factor Source: Ensembl
  6. response to peptide hormone Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
SLC45A3-BRAF fusion proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. neuron projection Source: Ensembl
  3. nucleus Source: Ensembl
  4. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiD7PBN4.
BgeeiD7PBN4.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliD7PBN4.

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7PBN4-1 [UniParc]FASTAAdd to Basket

« Hide

MKTLGRRDSS DDWEIPDGQI TVGQRIGSGS FGTVYKGKWH GDVAVKMLNV    50
TAPTPQQLQA FKNEVGVLRK TRHVNILLFM GYSTKPQLAI VTQWCEGSSL 100
YHHLHIIETK FEMIKLIDIA RQTAQGMDYL HAKSIIHRDL KSNNIFLHED 150
LTVKIGDFGL ATVKSRWSGS HQFEQLSGSI LWMAPEVIRM QDKNPYSFQS 200
DVYAFGIVLY ELMTGQLPYS NINNRDQIIF MVGRGYLSPD LSKVRSNCPK 250
AMKRLMAECL KKKRDERPLF PQILASIELL ARSLPKIHRS ASEPSLNRAG 300
FQTEDFSLYA CASPKTPIQA GGYGAFPVH 329
Length:329
Mass (Da):37,132
Last modified:August 10, 2010 - v1
Checksum:i93913670A7DEAB2C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GU149303 mRNA. Translation: ADH51735.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GU149303 mRNA. Translation: ADH51735.1 .

3D structure databases

ProteinModelPortali D7PBN4.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi D7PBN4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

NextBioi 35495686.

Gene expression databases

ArrayExpressi D7PBN4.
Bgeei D7PBN4.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF07714. Pkinase_Tyr. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD7PBN4_HUMAN
AccessioniPrimary (citable) accession number: D7PBN4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 14, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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