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Protein

Histone deacetylase

Gene

ARALYDRAFT_327775

Organism
Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei107SubstrateUniRule annotation1
Active sitei149Proton acceptorUniRule annotation1
Binding sitei157Substrate; via carbonyl oxygenUniRule annotation1
Metal bindingi184Divalent metal cationUniRule annotation1
Metal bindingi186Divalent metal cationUniRule annotation1
Metal bindingi272Divalent metal cationUniRule annotation1
Binding sitei311SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotationSAAS annotation, HydrolaseUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotationSAAS annotation (EC:3.5.1.98UniRule annotationSAAS annotation)
Gene namesi
ORF Names:ARALYDRAFT_327775Imported
OrganismiArabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress)Imported
Taxonomic identifieri81972 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000008694 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi59689.fgenesh1_pm.C_scaffold_7000002.

Structurei

3D structure databases

ProteinModelPortaliD7MEW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 324Hist_deacetylInterPro annotationAdd BLAST289

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

KOiK06067.
OrthoDBiEOG093609CH.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

D7MEW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTGGNSLAS GPDGVKRKVC YFYDPEVGNY YYGQGHPMKP HRIRMTHALL
60 70 80 90 100
AHYGLLQHMQ VLKPFPARDR DLCRFHADDY VSFLRSITPE TQQDQIRQLK
110 120 130 140 150
RFNVGEDCPV FDGLYSFCQT YAGGSVGGSV KLNHGLCDIA INWAGGLHHA
160 170 180 190 200
KKCEASGFCY VNDIVLAILE LLKQHERVLY VDIDIHHGDG VEEAFYATDR
210 220 230 240 250
VMTVSFHKFG DYFPGTGHIQ DIGYGNGKYY SLNVPLDDGI DDESYHLLFK
260 270 280 290 300
PIMGKVMEVF RPGAVVLQCG ADSLSGDRLG CFNLSIKGHA ECVKFMRSFN
310 320 330 340 350
VPLLLLGGGG YTIRNVARCW CYETGVALGV EVEDKMPEHE YYEYFGPDYT
360 370 380 390 400
LHVAPSNMEN KNSRQMLEEI RNDLLHNLSK LQHAPSVPFQ ERPPDTEAPE
410 420 430 440 450
VDEDQEDGDK RWDPDSDMDV DDDRKPIPSR VKREAVEPDT KDKDGLKGVM
460 470 480 490 500
ERGKGCEVGV DESGSSKVTG VNPVGMEEAS VKMEEEGTNK GGADQVFPKI
Length:500
Mass (Da):55,867
Last modified:August 10, 2010 - v1
Checksum:i771CE99F2454C6C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL348719 Genomic DNA. Translation: EFH45092.1.
RefSeqiXP_002868833.1. XM_002868787.1.

Genome annotation databases

EnsemblPlantsifgenesh1_pm.C_scaffold_7000002; fgenesh1_pm.C_scaffold_7000002; fgenesh1_pm.C_scaffold_7000002.
GeneIDi9304905.
Grameneifgenesh1_pm.C_scaffold_7000002; fgenesh1_pm.C_scaffold_7000002; fgenesh1_pm.C_scaffold_7000002.
KEGGialy:ARALYDRAFT_327775.

Similar proteinsi

Entry informationi

Entry nameiD7MEW2_ARALL
AccessioniPrimary (citable) accession number: D7MEW2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: August 30, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported