D7LWU5 (D7LWU5_ARALL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate synthase RuleBase RU000555
EC=2.3.3.9 RuleBase RU000555

Gene names

ORF Names:

ARALYDRAFT_660232 EMBL EFH49378.1

Organism

Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress) [Complete proteome]

Taxonomic identifier

81972 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis › Arabidopsis lyrata

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. RuleBase RU000555
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. RuleBase RU000555
Sequence similarities	Belongs to the malate synthase family. RuleBase RU000555

Ontologies

Keywords
Biological process	Glyoxylate bypass RuleBase RU000555 Tricarboxylic acid cycle RuleBase RU000555
Molecular function	Transferase RuleBase RU000555
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glyoxylate cycle Inferred from electronic annotation. Source: UniProtKB-UniPathway tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	malate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	177	1	Proton acceptor By similarity PIRSR PIRSR001363-1
	Active site	463	1	Proton donor By similarity PIRSR PIRSR001363-1

Sequences

	Sequence		Length	Mass (Da)
	D7LWU5 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: 39289EC085288697	FASTA	562	64,025
	10 20 30 40 50 60 MELETSVYRP NVAVYDSPDG VEVRGRYDQI FAKILTREAL NFVAELQREF RGHVRYAMEC 70 80 90 100 110 120 RREARRRYNS GAVPGFDPST KFIRDGDWIC ASVPPAVADR RVEITGPVER KMIINALNSG 130 140 150 160 170 180 AKVFMADFED ALSPSWENLM RGHVNLKDAV DGSITFHDKS RNRVYKLNDQ TAKLFVRPRG 190 200 210 220 230 240 WHLPEAHILI DGEPATGCLV DFGLYFFHNY AKFRQTQGSG FGPFFYLPKM EHSREAKIWN 250 260 270 280 290 300 SVFERAEKMA GIERGSIRAT VLIETLPAVF QMNEILYELR DHTVGLNCGR WDYIFSYVKT 310 320 330 340 350 360 FQAHPDRLLP DRVLVGMGQH FMRSYSDLLI RTCHKRGVHA MGGMAAQIPI RDDPKANEMA 370 380 390 400 410 420 LDLVRKDKLR EVRAGHDGTW AAHPGLIPIC MEAFTGHMGK SPNQIKSVKR EDAAAITEED 430 440 450 460 470 480 LLQIPRGVRT LEGLRLNTRV GIQYLAAWLT GSGSVPLYNL MEDAATAEIS RVQNWQWIRY 490 500 510 520 530 540 GVELDGDGLG VRVTKELFGR VVEEEMERIE KEVGKDKFKK GMYKEACKMF TKQCTAPELD 550 560 DFLTLAVYNH IVAHYPINNS RL

References

[1]

"The Arabidopsis lyrata genome sequence and the basis of rapid genome size change." Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M., Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G., Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K., Spannagl M., Wang X. , Yang L., Nasrallah M.E., Bergelson J., Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y., Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L. Nat. Genet. 43:476-481(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. MN47.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GL348718 Genomic DNA. Translation: EFH49378.1.
RefSeq	XP_002873119.1. XM_002873073.1.
3D structure databases
ProteinModelPortal	D7LWU5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9309187.
KEGG	aly:ARALYDRAFT_660232.
Phylogenomic databases
KO	K01638.
Enzyme and pathway databases
UniPathway	UPA00703; UER00720.
Family and domain databases
InterPro	IPR011076. Malate_synth-like. IPR006252. Malate_synthA. IPR001465. Malate_synthase. IPR019830. Malate_synthase_CS. [Graphical view]
PANTHER	PTHR21631:SF1. PTHR21631:SF1. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF001363. Malate_synth. 1 hit.
SUPFAM	SSF51645. Malat_synth_like. 1 hit.
TIGRFAMs	TIGR01344. malate_syn_A. 1 hit.
PROSITE	PS00510. MALATE_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D7LWU5_ARALL

Accession

Primary (citable) accession number: D7LWU5

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	January 9, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)