ID   D7LFS4_ARALL            Unreviewed;       654 AA.
AC   D7LFS4;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-NOV-2023, entry version 74.
DE   RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ARALYDRAFT_902401 {ECO:0000313|EMBL:EFH55704.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00358}.
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DR   EMBL; GL348716; EFH55704.1; -; Genomic_DNA.
DR   RefSeq; XP_002879445.1; XM_002879399.1.
DR   AlphaFoldDB; D7LFS4; -.
DR   STRING; 81972.D7LFS4; -.
DR   EnsemblPlants; scaffold_401902.1; scaffold_401902.1; scaffold_401902.1.
DR   GeneID; 9317341; -.
DR   Gramene; scaffold_401902.1; scaffold_401902.1; scaffold_401902.1.
DR   KEGG; aly:9317341; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   HOGENOM; CLU_004556_4_0_1; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0000792; C:heterochromatin; IEA:EnsemblPlants.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0080188; P:gene silencing by RNA-directed DNA methylation; IEA:EnsemblPlants.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   Gene3D; 2.30.280.10; SRA-YDG; 1.
DR   InterPro; IPR025794; H3-K9-MeTrfase_plant.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR036987; SRA-YDG_sf.
DR   InterPro; IPR003105; SRA_YDG.
DR   PANTHER; PTHR45660:SF81; HISTONE-LYSINE N-METHYLTRANSFERASE FAMILY MEMBER SUVH2; 1.
DR   PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF02182; SAD_SRA; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SMART; SM00466; SRA; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50890; PUA; 1.
DR   PROSITE; PS51575; SAM_MT43_SUVAR39_2; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS51015; YDG; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00358}; Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT   DOMAIN          210..357
FT                   /note="YDG"
FT                   /evidence="ECO:0000259|PROSITE:PS51015"
FT   DOMAIN          437..495
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          498..641
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
SQ   SEQUENCE   654 AA;  72793 MW;  81B786192BF757FB CRC64;
     MSTVVPFPDL NLMPASQSST AGTTAGDTVV TGKLEVKAEP VEECQTPPSS FSDQSASTDL
     IAEFIRISKL FRSAFKPHQI EGLDGVSVYG LDSGAIVTVP EEENRELIKP PPGFGDNRVS
     TVVVSPPPTK FERPRELARI AILGHDQRKE LRQVMKRTRM TYESLRIHLM AESMKNPVLG
     QGRRRRSDMA AAYIMRDRGL WLNYDKHIVG PISGVEIGDI FFYRMELCVV GLHGQTQAGI
     DCLTAERSAT GEPIATSIVV SGGYEDDEDT GDVLVYTGHG GQDKQHKQCD NQRLVGGNLG
     MERSMHYGIE VRVIRGIKYE NSISSKVYVY DGLYKIVDCW FAVGKSGFGV FKFRLVRMDG
     QPMMGSAVMR FAQTLRSKPL MVRPTGYVSF DLSNKKENVP VFLYNDVDGD QEPRHYEYIA
     KSVFPPGIFG QGGISRTGCD CKLSCTDDCL CARKNGGEFA YDDNGHLLRG KDVVFECGEL
     CTCGPNCKSR VTQKGLRNRL EVFRSKETGW GVRTLDLIEA GAFICEYAGV VVTRHQAEIL
     SMNGDVMVYP GRFTDKWRNW GDLSQVYPDS VRPDYPSLPP LDFAMDVSRM RNVACYISHS
     KDPNVMVQFV LYDHNHLMFP RVMLFALENI SPLAELSLDY GLADEVNGKL AICN
//