ID   D7KR71_ARALL            Unreviewed;       669 AA.
AC   D7KR71;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   24-JAN-2024, entry version 79.
DE   RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ARALYDRAFT_895166 {ECO:0000313|EMBL:EFH63731.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00358}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL348714; EFH63731.1; -; Genomic_DNA.
DR   RefSeq; XP_002887472.1; XM_002887426.1.
DR   AlphaFoldDB; D7KR71; -.
DR   STRING; 81972.D7KR71; -.
DR   EnsemblPlants; scaffold_202240.1; scaffold_202240.1; scaffold_202240.1.
DR   GeneID; 9323536; -.
DR   Gramene; scaffold_202240.1; scaffold_202240.1; scaffold_202240.1.
DR   KEGG; aly:9323536; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   HOGENOM; CLU_004556_2_1_1; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0010385; F:double-stranded methylated DNA binding; IEA:EnsemblPlants.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   Gene3D; 2.30.280.10; SRA-YDG; 1.
DR   InterPro; IPR025794; H3-K9-MeTrfase_plant.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR036987; SRA-YDG_sf.
DR   InterPro; IPR003105; SRA_YDG.
DR   PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   PANTHER; PTHR45660:SF24; HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH3-RELATED; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF02182; SAD_SRA; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SMART; SM00466; SRA; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS51575; SAM_MT43_SUVAR39_2; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS51015; YDG; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00358}; Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          208..355
FT                   /note="YDG"
FT                   /evidence="ECO:0000259|PROSITE:PS51015"
FT   DOMAIN          430..491
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          494..638
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          653..669
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
FT   REGION          32..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  72886 MW;  49D4B1E4B33860BF CRC64;
     MEGVPGVNTV PNPNHYDKSI VLDVKPLRSL KPVFPNGNQG PPFVGCPPFG PSSSGSSPFF
     PFGTQQPTQD TPDLNQTQDT PTPSFVPPLR SYRTPTETNG PSSSSGSKRG VGRPKGPSSV
     KKKEKKTVAN EPNLDVQVVK RFSSDFDSGI SPAEREDGNA YLVSSVLMRY DAVRRRLSQV
     EFAKAATSKA AGTLMSNGVR TNMKKRVGTV PGIEVGDIFF SRIEMCLVGL HMQTMAGIDY
     ITSKAGSDEE PLATSIVASG RYEGEAQDPE SLIYSGQGGN ADKNGQASDQ KLERGNLALE
     KSLRKGNGVR VIRGEEDAAT KTGKIYIYDG LYSISESWVE KGKSGCNTFK YKLVRLPGQP
     PAFGVWKSVQ KWKEGLTTRP GLILPDITSG AESKPVSLVN DVDEEKGPAY FTYISSLKYS
     DSFKLTQPAI GCSCSGSCAP GNLNCSCIRK NDGDLPYLNG VMLVSRRPII YECGPTCPCH
     ASCKNKVIQT GLKSRLEVFK TGNRGWGLRS WDSIRAGSFI CEYAGEVKDK GNLRGNQEED
     EYVFDTSRVF NSFKWNYEPE LVDEDPSDEV PEEFNLPSPL LISAKKFGNV ARFMNHSCSP
     NVFWQPVICE GNGESVIHIA FFAMRHIPPM AELTYDYGVS PTSEARDGSL LHGQRTCLCG
     SEQCRGSFG
//