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Protein

Beta-(1-->2)glucan export ATP-binding/permease protein NdvA

Gene

ndvA

Organism
Brucella abortus bv. 5 str. B3196
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in Beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.UniRule annotation

Catalytic activityi

ATP + H2O + beta-glucan(In) = ADP + phosphate + beta-glucan(Out).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi368 – 375ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processSugar transportUniRule annotation, Transport
LigandATP-bindingUniRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-(1-->2)glucan export ATP-binding/permease protein NdvAUniRule annotation (EC:3.6.3.42UniRule annotation)
Gene namesi
Name:ndvAUniRule annotation
ORF Names:BAYG_01271Imported
OrganismiBrucella abortus bv. 5 str. B3196Imported
Taxonomic identifieri520453 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000005752 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Transmembranei55 – 77HelicalSequence analysisAdd BLAST23
Transmembranei158 – 177HelicalSequence analysisAdd BLAST20
Transmembranei248 – 265HelicalSequence analysisAdd BLAST18
Transmembranei272 – 289HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD7H3E6.
SMRiD7H3E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 301ABC transmembrane type-1InterPro annotationAdd BLAST280
Domaini335 – 588NDVAInterPro annotationAdd BLAST254
Domaini335 – 569ABC transporterInterPro annotationAdd BLAST235

Domaini

In NdvA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.UniRule annotation

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

Gene3Di1.20.1560.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR017902. ABC_bGlucan_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR005896. NdvA.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR01192. chvA. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51317. NDVA. 1 hit.

Sequencei

Sequence statusi: Complete.

D7H3E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLKIYWRA MQYLAVERTA TITMCVASVL VALVTLAEPV LFGRVIQSIS
60 70 80 90 100
DKGDIFSPLL MWAALGGFNI MAAVFVARGA DRLAHRRRLG VMIDSYERLI
110 120 130 140 150
TMPLAWHQKR GTSNALHTLI RATDSLFTLW LEFMRQHLTT VVALATLIPV
160 170 180 190 200
AMTMDMRMSL VLIVLGVIYV MIGQLVMRKT KDGQAAVEKH HHKLFEHVSD
210 220 230 240 250
TISNVSVVQS YNRIASETQA LRDYAKNLEN AQFPVLNWWA LASGLNRMAS
260 270 280 290 300
TFSMVVVLVL GAYFVTKGQM RVGDVIAFIG FAQLMIGRLD QISAFINQTV
310 320 330 340 350
TARAKLEEFF QMEDATADRQ EPENVADLND VKGDIVFDNV TYEFPNSGQG
360 370 380 390 400
VYDVSFEVKP GQTVAIVGPT GAGKTTLINL LQRVFDPAAG RIMIDGTDTR
410 420 430 440 450
TVSRRSLRHA IATVFQDAGL FNRSVEDNIR VGRANATHEE VHAAAKAAAA
460 470 480 490 500
HDFILAKSEG YDTFVGERGS QLSGGERQRL AIARAILKDS PILVLDEATS
510 520 530 540 550
ALDVETEEKV TQAVDELSHN RTTFIIAHRL STVRSADLVL FMDKGHLVES
560 570 580 590
GSFNELAERG GRFSDLLRAG GLKLEDKQPK QPVVEGSNVM PFPVKGAVA
Length:599
Mass (Da):65,951
Last modified:August 10, 2010 - v1
Checksum:i2626C3220E57341C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG774511 Genomic DNA. Translation: EFH34839.1.

Genome annotation databases

EnsemblBacteriaiEFH34839; EFH34839; BAYG_01271.

Similar proteinsi

Entry informationi

Entry nameiD7H3E6_BRUAO
AccessioniPrimary (citable) accession number: D7H3E6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: October 25, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported