Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D7GM08

- D7GM08_HPV11

UniProt

D7GM08 - D7GM08_HPV11

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Major capsid protein L1

Gene

L1

Organism
Human papillomavirus type 11
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms an icosahedral capsid with a T=7 symmetry. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell.UniRule annotation

GO - Molecular functioni

  1. structural molecule activity Source: InterPro

GO - Biological processi

  1. viral entry into host cell Source: UniProtKB-KW
  2. virion attachment to host cell Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Viral attachment to host cellUniRule annotationSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein L1UniRule annotationSAAS annotation
Gene namesi
Name:L1Imported
Synonyms:L1(A)Imported
OrganismiHuman papillomavirus type 11Imported
Taxonomic identifieri10580 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePapillomaviridaeAlphapapillomavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

Virion UniRule annotation

GO - Cellular componenti

  1. T=7 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=7 icosahedral capsid proteinUniRule annotationSAAS annotation, Virion

Expressioni

Keywords - Developmental stagei

Late proteinUniRule annotation

Interactioni

Subunit structurei

Self-assembles into homopentamers. The capsid has an icosahedral symmetry and consists of 72 capsomers, with each capsomer being a pentamer of L1. Interacts with the minor capsid protein L2; this interaction is necessary for viral genome encapsidation.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD7GM08.
SMRiD7GM08. Positions 20-470.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the papillomaviridae L1 protein family.UniRule annotation

Family and domain databases

Gene3Di2.60.175.20. 1 hit.
InterProiIPR002210. Capsid_L1_Papillomavir.
IPR011222. dsDNA_vir_gr_I_capsid.
[Graphical view]
PfamiPF00500. Late_protein_L1. 1 hit.
[Graphical view]
PRINTSiPR00865. HPVCAPSIDL1.
SUPFAMiSSF88648. SSF88648. 1 hit.

Sequencei

Sequence statusi: Complete.

D7GM08-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWRPSDSTVY VPPPNPVSKV VATDAYVKRT NIFYHASSSR LLAVGHPYYS
60 70 80 90 100
IKKVNKTVVP KVSGYQYRVF KVVLPDPNKF ALPDSSLFDP TTQRLVWACT
110 120 130 140 150
GLEVGRGQPL GVGVSGHPLL NKYDDVENSG GYGGNPGQDN RVNVGMDYKQ
160 170 180 190 200
TQLCMVGCAP PLGEHWGKGT QCSNTSVQNG DCPPLELITS VIQDGDMVDT
210 220 230 240 250
GFGAMNFADL QTNKSDVPLD ICGTVCKYPD YLQMAADPYG DRLFFYLRKE
260 270 280 290 300
QMFARHFFNR AGTVGEPVPD DLLVKGGNNR SSVASSIYVH TPSGSLVSSE
310 320 330 340 350
AQLFNKPYWL QKAQGHNNGI CWGNHLFVTV VDTTRSTNMT LCASVSKSAT
360 370 380 390 400
YTNSDYKEYM RHVEEFDLQF IFQLCSITLS AEVMAYIHTM NPSVLEDWNF
410 420 430 440 450
GLSPPPNGTL EDTYRYVQSQ AITCQKPTPE KEKQDPYKDM SFWEVNLKEK
460 470 480 490 500
FSSELDQFPL GRKFLLQSGY RGRTSARTGI KRPAVSKPST APKRKRTKTK

K
Length:501
Mass (Da):55,835
Last modified:August 10, 2010 - v1
Checksum:i88957D023CC182A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN644141 Genomic DNA. Translation: AFC88068.1.
JN644142 Genomic DNA. Translation: AFC88076.1.
JQ773408 Genomic DNA. Translation: AFF57210.1.
JQ773409 Genomic DNA. Translation: AFF57219.1.
JQ773410 Genomic DNA. Translation: AFF57228.1.
JQ773411 Genomic DNA. Translation: AFF57237.1.
JQ773412 Genomic DNA. Translation: AFF57246.1.
FN870021 Genomic DNA. Translation: CBM41337.1.
FN870022 Genomic DNA. Translation: CBM41346.1.
FN870688 Genomic DNA. Translation: CBM41705.1.
FN870690 Genomic DNA. Translation: CBM41707.1.
FN870691 Genomic DNA. Translation: CBM41708.1.
FN870693 Genomic DNA. Translation: CBM41710.1.
FN870695 Genomic DNA. Translation: CBM41712.1.
FN870697 Genomic DNA. Translation: CBM41714.1.
FN870698 Genomic DNA. Translation: CBM41715.1.
FN870699 Genomic DNA. Translation: CBM41716.1.
FN870701 Genomic DNA. Translation: CBM41718.1.
FN870702 Genomic DNA. Translation: CBM41719.1.
FN870703 Genomic DNA. Translation: CBM41720.1.
FN870705 Genomic DNA. Translation: CBM41722.1.
FN870706 Genomic DNA. Translation: CBM41723.1.
FN870707 Genomic DNA. Translation: CBM41724.1.
FN870708 Genomic DNA. Translation: CBM41725.1.
FN870709 Genomic DNA. Translation: CBM41726.1.
FN870710 Genomic DNA. Translation: CBM41727.1.
FN870712 Genomic DNA. Translation: CBM41729.1.
FN870713 Genomic DNA. Translation: CBM41730.1.
FN870714 Genomic DNA. Translation: CBM41731.1.
FN870715 Genomic DNA. Translation: CBM41732.1.
FN870716 Genomic DNA. Translation: CBM41733.1.
FN870718 Genomic DNA. Translation: CBM41735.1.
FN870719 Genomic DNA. Translation: CBM41736.1.
FN870720 Genomic DNA. Translation: CBM41737.1.
FN870721 Genomic DNA. Translation: CBM41738.1.
FN870722 Genomic DNA. Translation: CBM41739.1.
FN870723 Genomic DNA. Translation: CBM41740.1.
FN870724 Genomic DNA. Translation: CBM41741.1.
FN870726 Genomic DNA. Translation: CBM41743.1.
FN870727 Genomic DNA. Translation: CBM41744.1.
FN870728 Genomic DNA. Translation: CBM41745.1.
FN870729 Genomic DNA. Translation: CBM41746.1.
FN870731 Genomic DNA. Translation: CBM41748.1.
FN870732 Genomic DNA. Translation: CBM41749.1.
FN870733 Genomic DNA. Translation: CBM41750.1.
FN870734 Genomic DNA. Translation: CBM41751.1.
FN870735 Genomic DNA. Translation: CBM41752.1.
FN870736 Genomic DNA. Translation: CBM41753.1.
FN870737 Genomic DNA. Translation: CBM41754.1.
FN870738 Genomic DNA. Translation: CBM41755.1.
FN870739 Genomic DNA. Translation: CBM41756.1.
FN870740 Genomic DNA. Translation: CBM41757.1.
FN870741 Genomic DNA. Translation: CBM41758.1.
FN870742 Genomic DNA. Translation: CBM41759.1.
FN870743 Genomic DNA. Translation: CBM41760.1.
FN870744 Genomic DNA. Translation: CBM41761.1.
FN870745 Genomic DNA. Translation: CBM41762.1.
FN870746 Genomic DNA. Translation: CBM41763.1.
FN870747 Genomic DNA. Translation: CBM41764.1.
FN870748 Genomic DNA. Translation: CBM41765.1.
FN870749 Genomic DNA. Translation: CBM41766.1.
FN870750 Genomic DNA. Translation: CBM41767.1.
FN907957 Genomic DNA. Translation: CBM41975.1.
FN907958 Genomic DNA. Translation: CBM41984.1.
FN907962 Genomic DNA. Translation: CBM42020.1.
FN907963 Genomic DNA. Translation: CBM42029.1.
FR872717 Genomic DNA. Translation: CCB84764.1.
HE574701 Genomic DNA. Translation: CCC55747.1.
HE574703 Genomic DNA. Translation: CCC55765.1.
HE574704 Genomic DNA. Translation: CCC55774.1.
HE574705 Genomic DNA. Translation: CCC55783.1.
HE611258 Genomic DNA. Translation: CCE60398.1.
HE611259 Genomic DNA. Translation: CCE60407.1.
HE611260 Genomic DNA. Translation: CCE60416.1.
HE611261 Genomic DNA. Translation: CCE60425.1.
HE611262 Genomic DNA. Translation: CCE60434.1.
HE611263 Genomic DNA. Translation: CCE60443.1.
HE611264 Genomic DNA. Translation: CCE60452.1.
HE611265 Genomic DNA. Translation: CCE60461.1.
HE611266 Genomic DNA. Translation: CCE60470.1.
HE611267 Genomic DNA. Translation: CCE60479.1.
HE611268 Genomic DNA. Translation: CCE60488.1.
HE611269 Genomic DNA. Translation: CCE60497.1.
HE611270 Genomic DNA. Translation: CCE60506.1.
HE611271 Genomic DNA. Translation: CCE60515.1.
HE611272 Genomic DNA. Translation: CCE60524.1.
HE611273 Genomic DNA. Translation: CCE60533.1.
HE611274 Genomic DNA. Translation: CCE60542.1.
HE962023 Genomic DNA. Translation: CCJ09304.1.
HE962024 Genomic DNA. Translation: CCJ09313.1.
HE962025 Genomic DNA. Translation: CCJ09322.1.
HE962365 Genomic DNA. Translation: CCJ09560.1.
HE962366 Genomic DNA. Translation: CCJ09569.1.
HE962367 Genomic DNA. Translation: CCJ09578.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN644141 Genomic DNA. Translation: AFC88068.1 .
JN644142 Genomic DNA. Translation: AFC88076.1 .
JQ773408 Genomic DNA. Translation: AFF57210.1 .
JQ773409 Genomic DNA. Translation: AFF57219.1 .
JQ773410 Genomic DNA. Translation: AFF57228.1 .
JQ773411 Genomic DNA. Translation: AFF57237.1 .
JQ773412 Genomic DNA. Translation: AFF57246.1 .
FN870021 Genomic DNA. Translation: CBM41337.1 .
FN870022 Genomic DNA. Translation: CBM41346.1 .
FN870688 Genomic DNA. Translation: CBM41705.1 .
FN870690 Genomic DNA. Translation: CBM41707.1 .
FN870691 Genomic DNA. Translation: CBM41708.1 .
FN870693 Genomic DNA. Translation: CBM41710.1 .
FN870695 Genomic DNA. Translation: CBM41712.1 .
FN870697 Genomic DNA. Translation: CBM41714.1 .
FN870698 Genomic DNA. Translation: CBM41715.1 .
FN870699 Genomic DNA. Translation: CBM41716.1 .
FN870701 Genomic DNA. Translation: CBM41718.1 .
FN870702 Genomic DNA. Translation: CBM41719.1 .
FN870703 Genomic DNA. Translation: CBM41720.1 .
FN870705 Genomic DNA. Translation: CBM41722.1 .
FN870706 Genomic DNA. Translation: CBM41723.1 .
FN870707 Genomic DNA. Translation: CBM41724.1 .
FN870708 Genomic DNA. Translation: CBM41725.1 .
FN870709 Genomic DNA. Translation: CBM41726.1 .
FN870710 Genomic DNA. Translation: CBM41727.1 .
FN870712 Genomic DNA. Translation: CBM41729.1 .
FN870713 Genomic DNA. Translation: CBM41730.1 .
FN870714 Genomic DNA. Translation: CBM41731.1 .
FN870715 Genomic DNA. Translation: CBM41732.1 .
FN870716 Genomic DNA. Translation: CBM41733.1 .
FN870718 Genomic DNA. Translation: CBM41735.1 .
FN870719 Genomic DNA. Translation: CBM41736.1 .
FN870720 Genomic DNA. Translation: CBM41737.1 .
FN870721 Genomic DNA. Translation: CBM41738.1 .
FN870722 Genomic DNA. Translation: CBM41739.1 .
FN870723 Genomic DNA. Translation: CBM41740.1 .
FN870724 Genomic DNA. Translation: CBM41741.1 .
FN870726 Genomic DNA. Translation: CBM41743.1 .
FN870727 Genomic DNA. Translation: CBM41744.1 .
FN870728 Genomic DNA. Translation: CBM41745.1 .
FN870729 Genomic DNA. Translation: CBM41746.1 .
FN870731 Genomic DNA. Translation: CBM41748.1 .
FN870732 Genomic DNA. Translation: CBM41749.1 .
FN870733 Genomic DNA. Translation: CBM41750.1 .
FN870734 Genomic DNA. Translation: CBM41751.1 .
FN870735 Genomic DNA. Translation: CBM41752.1 .
FN870736 Genomic DNA. Translation: CBM41753.1 .
FN870737 Genomic DNA. Translation: CBM41754.1 .
FN870738 Genomic DNA. Translation: CBM41755.1 .
FN870739 Genomic DNA. Translation: CBM41756.1 .
FN870740 Genomic DNA. Translation: CBM41757.1 .
FN870741 Genomic DNA. Translation: CBM41758.1 .
FN870742 Genomic DNA. Translation: CBM41759.1 .
FN870743 Genomic DNA. Translation: CBM41760.1 .
FN870744 Genomic DNA. Translation: CBM41761.1 .
FN870745 Genomic DNA. Translation: CBM41762.1 .
FN870746 Genomic DNA. Translation: CBM41763.1 .
FN870747 Genomic DNA. Translation: CBM41764.1 .
FN870748 Genomic DNA. Translation: CBM41765.1 .
FN870749 Genomic DNA. Translation: CBM41766.1 .
FN870750 Genomic DNA. Translation: CBM41767.1 .
FN907957 Genomic DNA. Translation: CBM41975.1 .
FN907958 Genomic DNA. Translation: CBM41984.1 .
FN907962 Genomic DNA. Translation: CBM42020.1 .
FN907963 Genomic DNA. Translation: CBM42029.1 .
FR872717 Genomic DNA. Translation: CCB84764.1 .
HE574701 Genomic DNA. Translation: CCC55747.1 .
HE574703 Genomic DNA. Translation: CCC55765.1 .
HE574704 Genomic DNA. Translation: CCC55774.1 .
HE574705 Genomic DNA. Translation: CCC55783.1 .
HE611258 Genomic DNA. Translation: CCE60398.1 .
HE611259 Genomic DNA. Translation: CCE60407.1 .
HE611260 Genomic DNA. Translation: CCE60416.1 .
HE611261 Genomic DNA. Translation: CCE60425.1 .
HE611262 Genomic DNA. Translation: CCE60434.1 .
HE611263 Genomic DNA. Translation: CCE60443.1 .
HE611264 Genomic DNA. Translation: CCE60452.1 .
HE611265 Genomic DNA. Translation: CCE60461.1 .
HE611266 Genomic DNA. Translation: CCE60470.1 .
HE611267 Genomic DNA. Translation: CCE60479.1 .
HE611268 Genomic DNA. Translation: CCE60488.1 .
HE611269 Genomic DNA. Translation: CCE60497.1 .
HE611270 Genomic DNA. Translation: CCE60506.1 .
HE611271 Genomic DNA. Translation: CCE60515.1 .
HE611272 Genomic DNA. Translation: CCE60524.1 .
HE611273 Genomic DNA. Translation: CCE60533.1 .
HE611274 Genomic DNA. Translation: CCE60542.1 .
HE962023 Genomic DNA. Translation: CCJ09304.1 .
HE962024 Genomic DNA. Translation: CCJ09313.1 .
HE962025 Genomic DNA. Translation: CCJ09322.1 .
HE962365 Genomic DNA. Translation: CCJ09560.1 .
HE962366 Genomic DNA. Translation: CCJ09569.1 .
HE962367 Genomic DNA. Translation: CCJ09578.1 .

3D structure databases

ProteinModelPortali D7GM08.
SMRi D7GM08. Positions 20-470.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.175.20. 1 hit.
InterProi IPR002210. Capsid_L1_Papillomavir.
IPR011222. dsDNA_vir_gr_I_capsid.
[Graphical view ]
Pfami PF00500. Late_protein_L1. 1 hit.
[Graphical view ]
PRINTSi PR00865. HPVCAPSIDL1.
SUPFAMi SSF88648. SSF88648. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Virological failure of intralesional cidofovir therapy in recurrent respiratory papillomatosis is not associated with genetic or epigenetic changes of HPV11: Complete genome comparison of sequential isolates."
    Gall T., Kis A., Feher E., Gergely L., Szarka K.
    Antiviral Res. 0:0-0(2011)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Prevaccination genomic diversity of human papillomavirus genotype 11: a study on 63 clinical isolates and 10 full-length genome sequences."
    Maver P.J., Kocjan B.J., Seme K., Gale N., Potonik M., Poljak M.
    J. Med. Virol. 83:461-470(2011)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A101Imported, A107Imported, A128Imported, A129Imported, A136Imported, A140Imported, A171Imported, A187Imported, A197Imported, A200Imported, A201Imported, A202Imported, A205Imported, A218Imported, A250Imported, A253Imported, A260Imported, A281Imported, A297Imported, A32Imported, A320Imported, A34Imported, A345Imported, A346Imported, A35Imported, A383Imported, A409Imported, A41Imported, A418Imported, A50Imported, A51Imported, A63Imported, A86Imported, A89Imported, CAC11Imported, CAC256Imported, CAC266Imported, CAC321Imported, CAC336Imported, CAC346Imported, CAC86Imported, CS123Imported, CS20Imported, CS58Imported, CS93Imported, LP1Imported, LP12Imported, LP14Imported, LP16Imported, LP19Imported, LP27Imported, LP6Imported and M3Imported.
  3. "Complete genome analysis of human papillomavirus type 11 from recurrent respiratory papillomatoses with different aggressivity."
    Gall T., Kis A., Feher E., Gergely L., Szarka K.
    Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JO-RRP_1Imported, JO-RRP_3Imported, JO-RRP_4Imported and JO-RRP_5Imported.
  4. "Tumor progression of recurrent respiratory papillomatosis: duplications in the HPV-11 genome and selection of a successful chemotherapeutic agent."
    Yuan H., Liu X., Wang J., Zhou D., Schlegel R.
    Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUMC-AJ-LungImported.
  5. "Whole genome analysis of human papillomavirus genotype 11 from cervix, larynx and lung."
    Chansaenroj J., Theamboonlers A., Junyangdikul P., Supiyaphan P., Poovorawan Y.
    Asian Pac. J. Cancer Prev. 13:2619-2623(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CU16Imported, CU17Imported, CU18Imported, CU19Imported and CU20Imported.
  6. "Divergent human papillomavirus associated with recurrent respiratory papillomatosis with lung involvement."
    Yuan H., Zhou D., Wang J., Schlegel R.
    Genome Announc. 1:E00474-13(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUMC-AJImported.
  7. "Identical human papillomavirus (HPV) genomic variants persist in recurrent respiratory papillomatosis for up to 22 years."
    Kocjan B.J., Gale N., Hocevar Boltezar I., Seme K., Fujs Komlos K., Hosnjak L., Maver P.J., Jelen M.M., Zupanic Pajnic I., Balazic J., Poljak M.
    J. Infect. Dis. 207:583-587(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: LP1Imported, LP126Imported, LP133Imported, LP138Imported, LP14Imported, LP146Imported, LP16Imported, LP170Imported, LP174Imported, LP19Imported, LP2Imported, LP20Imported, LP220Imported, LP221Imported, LP224fImported, LP229Imported, LP253fImported, LP262fImported, LP27Imported, LP6Imported, LP8Imported, LPX27Imported and LPX35Imported.

Entry informationi

Entry nameiD7GM08_HPV11
AccessioniPrimary (citable) accession number: D7GM08
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: November 26, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)