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D7FF07 (D7FF07_HELP3) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length641 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate By similarity. RuleBase RU004996

Catalytic activity

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate. RuleBase RU004996

Cofactor

Binds 1 magnesium ion per subunit. Can also utilize other divalent metal cations, such as Ca2+, Mn2+ and Co2+ By similarity. RuleBase RU004996

Binds 1 thiamine pyrophosphate per subunit By similarity. RuleBase RU004996

Subunit structure

Homodimer By similarity. RuleBase RU004996

Sequence similarities

Belongs to the transketolase family. RuleBase RU004996

Sequences

Sequence LengthMass (Da)Tools
D7FF07 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 8C9B8386101E00B1

FASTA64170,670
        10         20         30         40         50         60 
MRLSNADLER LKSMANTLRF LCADMIDKAN SGHPGVCLGL ADVMVVLSLH LNLNPINPKW 

        70         80         90        100        110        120 
LNRDRLVFSG GHASALAYSL LHLWGFDLSL EDLKHFRQLH SKTPGHPELH HTEGIEITTG 

       130        140        150        160        170        180 
PLGQGFANAV GFSMASQYAQ NLLDKEVISH KVYCLCGDGD LQEGISYESA SLAGHLRLDN 

       190        200        210        220        230        240 
LIVIYDSNQI SIEGAINISF SEQVKTRFLA QNWEVLECDG HDYQAIHNAL EEAKKSHKPT 

       250        260        270        280        290        300 
LLIAHTIIGK GAVGLEGSEK THGSPLNKEV LKQSKENAQI NPDESFIISP KNKMHFEEVK 

       310        320        330        340        350        360 
VRGASLEALW EKSLSPKTKE KIHALKDFDF STIHYPTFKK GESLATRVSN GMILNAIAKE 

       370        380        390        400        410        420 
CEGFLGGSAD LAPSNNTQLK HSGDFPLGQN LHFGIREHAM GAITNALAAY GLFLPFCATF 

       430        440        450        460        470        480 
FVFSDYLMPS MRLSALMKLK ALFIFTHDSI GVGEDGATHQ PIEQLSHLRA LPNFYAFRPS 

       490        500        510        520        530        540 
DAFENKACMQ VALSLNAPSG LILSRQNLPV LDEVSKERVL KGAYVKYDAK DPIITLVASG 

       550        560        570        580        590        600 
SEISLALESA KMLERENIPT QVVSAPCFDL LIEQDESYLK ELFKGKVLVI EASRAIEWYR 

       610        620        630        640 
FADKIIGMDS FGSSAKGDKL FEKFGFSVEN ITAQAKRLLN A 

« Hide

References

[1]"Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8."
Farnbacher M., Jahns T., Willrodt D., Daniel R., Haas R., Goesmann A., Kurtz S., Rieder G.
BMC Genomics 11:335-335(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B8 EMBL CBI66764.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN598874 Genomic DNA. Translation: CBI66764.1.
RefSeqYP_003729228.1. NC_014256.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBI66764; CBI66764; HPB8_1207.
GeneID9350183.
KEGGhpl:HPB8_1207.
PATRIC38176717. VBIHelPyl164240_1163.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000225954.
KOK00615.
OMAPMGMAPI.

Enzyme and pathway databases

BioCycHPYL693745:GJAE-1228-MONOMER.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
3.40.50.970. 2 hits.
InterProIPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005478. Transketolase_bac-like.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsTIGR00232. tktlase_bact. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD7FF07_HELP3
AccessionPrimary (citable) accession number: D7FF07
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)