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D7E8Z9 (RIBL_METEZ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Metev_1061
OrganismMethanohalobium evestigatum (strain DSM 3721 / OCM 161 / Z-7303) [Complete proteome] [HAMAP]
Taxonomic identifier644295 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanohalobium

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 150150FAD synthase HAMAP-Rule MF_02115
PRO_0000406262

Regions

Nucleotide binding20 – 212ATP By similarity
Nucleotide binding25 – 284ATP By similarity
Nucleotide binding101 – 1044ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
D7E8Z9 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 4A565816BEFB8437

FASTA15016,837
        10         20         30         40         50         60 
MSLLKLCKGD LLTRVLATGT FDLLHPGHLH YLSEARKLGN ELYVIVARES MIKHKPKPVI 

        70         80         90        100        110        120 
PENQRVTMVN SLDVVDKAVL GSETNIYEPI KNIKPDVITI GYDQKFSSDS IEKNLEELGI 

       130        140        150 
NAKVVRINKL SDCSLCSSGK IIDRILERYC 

« Hide

References

[1]"Complete sequence chromosome of Methanohalobium evestigatum Z-7303."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I., Woyke T.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 3721 / OCM 161 / Z-7303.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002069 Genomic DNA. Translation: ADI73947.1.
RefSeqYP_003726743.1. NC_014253.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI73947; ADI73947; Metev_1061.
GeneID9346691.
KEGGmev:Metev_1061.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAIVLGHDQ.

Enzyme and pathway databases

BioCycMEVE644295:GHG3-1085-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METEZ
AccessionPrimary (citable) accession number: D7E8Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: August 10, 2010
Last modified: May 14, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways