ID   D7E131_NOSA0            Unreviewed;       637 AA.
AC   D7E131;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ADI63160.1};
GN   OrderedLocusNames=Aazo_0695 {ECO:0000313|EMBL:ADI63160.1};
OS   Nostoc azollae (strain 0708) (Anabaena azollae (strain 0708)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
OC   Trichormus.
OX   NCBI_TaxID=551115 {ECO:0000313|EMBL:ADI63160.1, ECO:0000313|Proteomes:UP000001511};
RN   [1] {ECO:0000313|EMBL:ADI63160.1, ECO:0000313|Proteomes:UP000001511}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0708 {ECO:0000313|EMBL:ADI63160.1,
RC   ECO:0000313|Proteomes:UP000001511};
RX   PubMed=20628610; DOI=10.1371/journal.pone.0011486;
RA   Ran L., Larsson J., Vigil-Stenman T., Nylander J.A., Ininbergs K.,
RA   Zheng W.W., Lapidus A., Lowry S., Haselkorn R., Bergman B.;
RT   "Genome erosion in a nitrogen-fixing vertically transmitted endosymbiotic
RT   multicellular cyanobacterium.";
RL   PLoS ONE 5:E11486-E11486(2010).
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DR   EMBL; CP002059; ADI63160.1; -; Genomic_DNA.
DR   AlphaFoldDB; D7E131; -.
DR   STRING; 551115.Aazo_0695; -.
DR   KEGG; naz:Aazo_0695; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 9787983at2; -.
DR   Proteomes; UP000001511; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001511};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          229..362
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          371..626
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   637 AA;  72422 MW;  536EBF6D954B5852 CRC64;
     MIIFMIGVIT GVGIQLISLS LFNFFVTKFS ENQPKKQQNN NLNFTESEGY LSIKLDKEIS
     ECQRIQPELQ KLLLLQKATL ESATDAILIV DSLDKIVGFN KKFLEMWDIP ALMITSGNYK
     QALRTAIKKL DNPRHYLSIL RELDENPDIH IGENILFKDG RIFNPFYQQQ YKYKKNIGQV
     WIFRDITAEK LASNIINYES LHDILTNLPN RLLLKNLLID ALTKVSHNHS LGVCFLDLDR
     FKKINDSLGH GIGDKLLQMV AQCIKKSLRS DDIVARWGGD EFIILLPEIS EMYNIDLIQE
     RIFAAFKQGF KIDNYHLNIS PSIGIALYPQ HGEDGETLIK NAEAALSFVK LQGRNNYKVY
     QAAINSQATE LFILENSLYN ALERQEFKVY YQPQVNSSTG EITKMEALLR WQHPELGLIP
     PATFIPIAEE TGLILPISEW VLKTACLQNK AWQQTLNLSS LSVAVNFSGR QFQQPNLVGI
     VEQVLCETKL AHRYLELEIT ETVAMQDVEL TQKILRQLDE MGVTISIDDF GTGYSSLSYL
     KDFSIHALKI DQSFVQDLAN KDHQTAITTA IISLAHGLNL SVVAEGVETQ EQLNALRILQ
     CEIMQGYFFS HPLSAEEATR MLTAYQPHRL KDSYLLA
//