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Protein

FAD synthase

Gene

ribL

Organism
Methanococcus voltae (strain ATCC BAA-1334 / A3)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.UniRule annotation

Catalytic activityi

ATP + FMN = diphosphate + FAD.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471ATP; via amide nitrogenUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi34 – 352ATPUniRule annotation
Nucleotide bindingi39 – 424ATPUniRule annotation
Nucleotide bindingi117 – 1204ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, FAD, Flavoprotein, FMN, Nucleotide-binding

Enzyme and pathway databases

BioCyciMVOL456320:GHV9-902-MONOMER.
UniPathwayiUPA00277; UER00407.

Names & Taxonomyi

Protein namesi
Recommended name:
FAD synthaseUniRule annotation (EC:2.7.7.2UniRule annotation)
Alternative name(s):
FMN adenylyltransferaseUniRule annotation
Flavin adenine dinucleotide synthaseUniRule annotation
Gene namesi
Name:ribLUniRule annotation
Ordered Locus Names:Mvol_0889
OrganismiMethanococcus voltae (strain ATCC BAA-1334 / A3)
Taxonomic identifieri456320 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000007722 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 174174FAD synthasePRO_0000406259Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the archaeal FAD synthase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000284153.
KOiK14656.
OMAiFAKKHAD.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_02115. FAD_synth_arch.
InterProiIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

D7DTT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIVIIMPKN ENNPNIKNNN HQSPKKRIAL TAGTFDLLHP GHFNTLNFAK
60 70 80 90 100
KHADELVVVL ARDETVKRIK GRRPVIPEEQ RKIMIETLKP VDKAILGSLT
110 120 130 140 150
DKLEPILSVK PDIIVLGPDQ TTYQLEELKN QLLERGFKTE IVKVEEYVKC
160 170
PFHSSYDILK EIIRRWCNKE IELK
Length:174
Mass (Da):20,126
Last modified:August 10, 2010 - v1
Checksum:i3D6F130CE09A6C98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002057 Genomic DNA. Translation: ADI36548.1.
RefSeqiWP_013180276.1. NC_014222.1.
YP_003707521.1. NC_014222.1.

Genome annotation databases

EnsemblBacteriaiADI36548; ADI36548; Mvol_0889.
GeneIDi9276111.
KEGGimvo:Mvol_0889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002057 Genomic DNA. Translation: ADI36548.1.
RefSeqiWP_013180276.1. NC_014222.1.
YP_003707521.1. NC_014222.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADI36548; ADI36548; Mvol_0889.
GeneIDi9276111.
KEGGimvo:Mvol_0889.

Phylogenomic databases

HOGENOMiHOG000284153.
KOiK14656.
OMAiFAKKHAD.

Enzyme and pathway databases

UniPathwayiUPA00277; UER00407.
BioCyciMVOL456320:GHV9-902-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_02115. FAD_synth_arch.
InterProiIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Methanococcus voltae A3."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Lowry S., Clum A., Land M., Hauser L., Kyrpides N., Mikhailova N., Whitman W.B., Woyke T.
    Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1334 / A3.

Entry informationi

Entry nameiRIBL_METV3
AccessioniPrimary (citable) accession number: D7DTT8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: August 10, 2010
Last modified: May 27, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.