Skip Header

Contribute Send feedback
Read comments (?) or add your own

D7DR14 (D7DR14_METV3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HAMAP-Rule MF_01014 RuleBase RU003658
EC=5.3.1.16 HAMAP-Rule MF_01014 RuleBase RU003658
Alternative name(s):
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HAMAP-Rule MF_01014
Gene names
Name:hisA HAMAP-Rule MF_01014
Ordered Locus Names:Mvol_1636
OrganismMethanococcus voltae (strain ATCC BAA-1334 / A3) [Complete proteome] [HAMAP] EMBL ADI37291.1
Taxonomic identifier456320 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus ›

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)-1-(5-phosphoribosyl)imidazole-4-carboxamide. HAMAP-Rule MF_01014 RuleBase RU003658

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9. HAMAP-Rule MF_01014 RuleBase RU003658

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01014 RuleBase RU003658.

Sequence similarities

Belongs to the HisA/HisF family. HAMAP-Rule MF_01014 RuleBase RU003657

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site81Proton acceptor By similarity HAMAP-Rule MF_01014
Active site1301Proton donor By similarity HAMAP-Rule MF_01014

Sequences

Sequence LengthMass (Da)Tools
D7DR14 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 65C019597A5B8CB0

FASTA24226,377
        10         20         30         40         50         60 
MDIIPAVDMK EGKCVQLIQG DPTKRHVEYD NPDEIAKMWV ENGAEMLHLV DLDGAIDGER 

        70         80         90        100        110        120 
VNLPMVKKII QESKVPVQMG GGIRTIEDVE ELVNLGINRV IIGTVAVQNP DFVEKLAKKV 

       130        140        150        160        170        180 
GSEKIMVALD AKDGKVVIKG WKEKTEYTPV QMGKILEEKG AGSILFTNVD SEGLLNGINI 

       190        200        210        220        230        240 
TPTKELVDNL NIPIIASGGV TTIDDLIEFK KIGVSGVVVG SALYKNNFKL NDAIITVNNF 


KL

« Hide

References

[1]"Complete sequence of Methanococcus voltae A3."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Lowry S., Clum A., Land M., Hauser L., Kyrpides N., Mikhailova N., Whitman W.B., Woyke T.
Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1334 / A3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002057 Genomic DNA. Translation: ADI37291.1.
RefSeqYP_003708264.1. NC_014222.1.

3D structure databases

ProteinModelPortalD7DR14.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI37291; ADI37291; Mvol_1636.
GeneID9276888.
KEGGmvo:Mvol_1636.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224614.
KOK01814.
OMADGHCVRL.

Enzyme and pathway databases

BioCycMVOL456320:GHV9-1680-MONOMER.
UniPathwayUPA00031; UER00009.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01014. HisA.
InterProIPR013785. Aldolase_TIM.
IPR006062. His_biosynth.
IPR006063. HisA.
IPR023016. Isoase_HisA.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00977. His_biosynth. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMsTIGR00007. TIGR00007. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD7DR14_METV3
AccessionPrimary (citable) accession number: D7DR14
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info