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D7DQ55

- D7DQ55_METV0

UniProt

D7DQ55 - D7DQ55_METV0

Protein

Alanine racemase

Gene

M301_1042

Organism
Methylotenera versatilis (strain 301)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei130 – 1301SubstrateUniRule annotation
    Active sitei251 – 2511Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei299 – 2991Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMVER666681:GHRP-1074-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:M301_1042Imported
    OrganismiMethylotenera versatilis (strain 301)Imported
    Taxonomic identifieri666681 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylotenera
    ProteomesiUP000000383: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD7DQ55.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiNITIISM.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D7DQ55-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSRPAIAHIR LDAFRHNYRV AKQAHAGKAL AVIKANAYGH GAVHCAKAIE    50
    GEADGFAVAC LEEALQLREA GIPEPILLLE GFFEAIELPE IVANDLWIVV 100
    HAQWQVEILF AAKLAKPLHV WLKMDSGMHR VGLPPDEYVQ AYERLKNHKN 150
    VGKIVLMTHF ANADNVSSNH TLQQIETFQN TTQGLSAEIS LANSAAILGW 200
    KQAKCDWTRP GIMLYGADPL MKADAKLKPV MQLTSKIISI SNVKQGESIG 250
    YGSIFTAERD TVVGVVACGY ADGYPRSAVT GTPIAVDGKM TRLIGRVSMD 300
    MLFVDLTDIP NATIGSQVEL WGNQVSANAV ATSAGTIAYE LFCNVKRAHF 350
    QYFDAANI 358
    Length:358
    Mass (Da):38,954
    Last modified:August 10, 2010 - v1
    Checksum:i856B39B47040417A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002056 Genomic DNA. Translation: ADI29426.1.
    RefSeqiYP_003674003.1. NC_014207.1.

    Genome annotation databases

    EnsemblBacteriaiADI29426; ADI29426; M301_1042.
    GeneIDi9396223.
    KEGGimeh:M301_1042.
    PATRICi38198451. VBIMetSp140979_1060.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002056 Genomic DNA. Translation: ADI29426.1 .
    RefSeqi YP_003674003.1. NC_014207.1.

    3D structure databases

    ProteinModelPortali D7DQ55.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI29426 ; ADI29426 ; M301_1042 .
    GeneIDi 9396223.
    KEGGi meh:M301_1042.
    PATRICi 38198451. VBIMetSp140979_1060.

    Phylogenomic databases

    KOi K01775.
    OMAi NITIISM.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci MVER666681:GHRP-1074-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Methylotenera sp. 301."
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Clum A., Land M., Hauser L., Kyrpides N., Ivanova N., Chistoservova L., Kalyuzhnaya M., Woyke T.
      Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 301Imported.

    Entry informationi

    Entry nameiD7DQ55_METV0
    AccessioniPrimary (citable) accession number: D7DQ55
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3