Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongation factor Tu

Gene

tuf

Organism
Methylotenera versatilis (strain 301)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMVER666681:GHRP-340-MONOMER.
MVER666681:GHRP-353-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:M301_0322Imported, M301_0334Imported
OrganismiMethylotenera versatilis (strain 301)Imported
Taxonomic identifieri666681 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylotenera
ProteomesiUP000000383 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi666681.M301_0334.

Structurei

3D structure databases

ProteinModelPortaliD7DLM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7DLM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AITTILSKKF GGEAKAYDQI
60 70 80 90 100
DAAPEEKARG ITINTAHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IVVYLNKADL VDDAELLELV
160 170 180 190 200
EMEVRDLLSK YDFPGDDTPI ITGSARAALE GDQTEIGEPS IFRLADALDN
210 220 230 240 250
YIPMPERAID GTFLMPVEDV FSISGRGTVV TGRIERGIIK VGEEIEIVGL
260 270 280 290 300
KPTVKTTCTG VEMFRKLLDQ GMAGDNVGVL LRGTKREDIE RGQVLAKSGS
310 320 330 340 350
IKPHTKFTAE IYVLGKDEGG RHTPFFQGYR PQFYFRTTDV TGAVELPAGT
360 370 380 390
EMVMPGDNVS ITVTLISPIA MEEGLRFAIR EGGRTVGAGV VAKIIE
Length:396
Mass (Da):42,899
Last modified:August 10, 2010 - v1
Checksum:iC93FC509B17F0DD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002056 Genomic DNA. Translation: ADI28709.1.
CP002056 Genomic DNA. Translation: ADI28721.1.
RefSeqiWP_013147026.1. NC_014207.1.

Genome annotation databases

EnsemblBacteriaiADI28709; ADI28709; M301_0322.
ADI28721; ADI28721; M301_0334.
KEGGimeh:M301_0322.
meh:M301_0334.
PATRICi38196945. VBIMetSp140979_0320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002056 Genomic DNA. Translation: ADI28709.1.
CP002056 Genomic DNA. Translation: ADI28721.1.
RefSeqiWP_013147026.1. NC_014207.1.

3D structure databases

ProteinModelPortaliD7DLM5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi666681.M301_0334.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADI28709; ADI28709; M301_0322.
ADI28721; ADI28721; M301_0334.
KEGGimeh:M301_0322.
meh:M301_0334.
PATRICi38196945. VBIMetSp140979_0320.

Phylogenomic databases

KOiK02358.

Enzyme and pathway databases

BioCyciMVER666681:GHRP-340-MONOMER.
MVER666681:GHRP-353-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequence of Methylotenera sp. 301."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Clum A., Land M., Hauser L., Kyrpides N., Ivanova N., Chistoservova L., Kalyuzhnaya M., Woyke T.
    Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 301Imported.
  2. "Genomes of three methylotrophs from a single niche reveal the genetic and metabolic divergence of the methylophilaceae."
    Lapidus A., Clum A., Labutti K., Kaluzhnaya M.G., Lim S., Beck D.A., Glavina Del Rio T., Nolan M., Mavromatis K., Huntemann M., Lucas S., Lidstrom M.E., Ivanova N., Chistoserdova L.
    J. Bacteriol. 193:3757-3764(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 301Imported.

Entry informationi

Entry nameiD7DLM5_METV0
AccessioniPrimary (citable) accession number: D7DLM5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: July 22, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.