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D7DLK3 (D7DLK3_METS0) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111

EC=2.5.1.7 HAMAP-Rule MF_00111
Alternative name(s):
Enoylpyruvate transferase HAMAP-Rule MF_00111
UDP-N-acetylglucosamine enolpyruvyl transferase HAMAP-Rule MF_00111
Gene names
Name:murA HAMAP-Rule MF_00111
Ordered Locus Names:M301_0300 EMBL ADI28687.1
OrganismMethylotenera sp. (strain 301) [Complete proteome] [HAMAP] EMBL ADI28687.1
Taxonomic identifier666681 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylotenera

Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111 SAAS SAAS005750

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111 SAAS SAAS005750

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00111 SAAS SAAS005750.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily. HAMAP-Rule MF_00111

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1161Proton donor By similarity HAMAP-Rule MF_00111

Amino acid modifications

Modified residue11612-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity HAMAP-Rule MF_00111

Sequences

Sequence LengthMass (Da)Tools
D7DLK3 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: F3EAE8D3D5DB2685

FASTA42044,622
        10         20         30         40         50         60 
MEKLIIQGGS RLNGEVTISG AKNAALPILC ASLLAETPLH LSSIAALKDI DTTIKLLDMM 

        70         80         90        100        110        120 
GVKITRNTSE VTLDASDVTS FEATYEMVKT MRASILVLGP LLARFGTARV SLPGGCAIGS 

       130        140        150        160        170        180 
RPVDLHIKGL QAMGAAIHIT HGYIQASTLH LPNRRLQGAR YYMDMVTVTG TENLMMAAAL 

       190        200        210        220        230        240 
AEGTTVLENA AKEPEVVDLA EMLIKMGAKI TGAGTDVITI VGVEKLNGTT HNVVCDRIEA 

       250        260        270        280        290        300 
GTYMVAAAMT GGEVKLLNAR ADLLDAVIEK LRDAGATVTS DANSITVKSD GKLKAVNIRT 

       310        320        330        340        350        360 
APHPAFPTDM QAQFMALNVI AEGVSKVTET IFENRFMHVQ EMQRMGADIS IDGNTALVKG 

       370        380        390        400        410        420 
IEFLDGATVM ATDLRASASL VLAGLVARGE TVIERIYHLD RGYEHLEAKL NALGANVKRV 

« Hide

References

[1]"Complete sequence of Methylotenera sp. 301."
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Clum A., Land M., Hauser L., Kyrpides N., Ivanova N., Chistoservova L., Kalyuzhnaya M., Woyke T.
Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002056 Genomic DNA. Translation: ADI28687.1.
RefSeqYP_003673264.1. NC_014207.1.

3D structure databases

ProteinModelPortalD7DLK3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI28687; ADI28687; M301_0300.
GeneID9395956.
KEGGmeh:M301_0300.
PATRIC38196893. VBIMetSp140979_0298.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00790.
OMASIWALAP.

Enzyme and pathway databases

BioCycMVER666681:GHRP-314-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD7DLK3_METS0
AccessionPrimary (citable) accession number: D7DLK3
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)