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D7DGR8

- D7DGR8_CHLTL

UniProt

D7DGR8 - D7DGR8_CHLTL

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Protein
Elongation factor Tu
Gene
tuf, CTDLC_0322
Organism
Chlamydia trachomatis serovar D (strain D-LC)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi24 – 318GTP By similarityUniRule annotation
Nucleotide bindingi86 – 905GTP By similarityUniRule annotation
Nucleotide bindingi141 – 1444GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTRA759364:GLAV-331-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:CTDLC_0322Imported
OrganismiChlamydia trachomatis serovar D (strain D-LC)Imported
Taxonomic identifieri759364 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000382: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD7DGR8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7DGR8-1 [UniParc]FASTAAdd to Basket

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MRIFEMSKET FQRNKPHINI GTIGHVDHGK TTLTAAITRA LSGDGLADFR    50
DYSSIDNTPE EKARGITINA SHVEYETANR HYAHVDCPGH ADYVKNMITG 100
AAQMDGAILV VSATDGAMPQ TKEHILLARQ VGVPYIVVFL NKIDMISEED 150
AELVDLVEME LVELLEEKGY KGCPIIRGSA LKALEGDAAY IEKVRELMQA 200
VDDNIPTPER EIDKPFLMPI EDVFSISGRG TVVTGRIERG IVKVSDKVQL 250
VGLRDTKETI VTGVEMFRKE LPEGRAGENV GLLLRGIGKN DVERGMVVCL 300
PNSVKPHTQF KCAVYVLQKE EGGRHKPFFT GYRPQFFFRT TDVTGVVTLP 350
EGIEMVMPGD NVEFEVQLIS PVALEEGMRF AIREGGRTIG AGTISKIIA 399
Length:399
Mass (Da):43,969
Last modified:August 10, 2010 - v1
Checksum:iB507303F29FB2A98
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002054 Genomic DNA. Translation: ADI52009.1.
RefSeqiWP_014541402.1. NC_017436.1.
YP_005812252.1. NC_017436.1.

Genome annotation databases

EnsemblBacteriaiADI52009; ADI52009; CTDLC_0322.
GeneIDi12387806.
KEGGictf:CTDLC_0322.
PATRICi42818551. VBIChlTra159408_0346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002054 Genomic DNA. Translation: ADI52009.1 .
RefSeqi WP_014541402.1. NC_017436.1.
YP_005812252.1. NC_017436.1.

3D structure databases

ProteinModelPortali D7DGR8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADI52009 ; ADI52009 ; CTDLC_0322 .
GeneIDi 12387806.
KEGGi ctf:CTDLC_0322.
PATRICi 42818551. VBIChlTra159408_0346.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.

Enzyme and pathway databases

BioCyci CTRA759364:GLAV-331-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract."
    Sturdevant G.L., Kari L., Gardner D.J., Olivares-Zavaleta N., Randall L.B., Whitmire W.M., Carlson J.H., Goheen M.M., Selleck E.M., Martens C., Caldwell H.D.
    Infect. Immun. 78:3660-3668(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D-LCImported.

Entry informationi

Entry nameiD7DGR8_CHLTL
AccessioniPrimary (citable) accession number: D7DGR8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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