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D7DAC8 (D7DAC8_STAHD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase HAMAP-Rule MF_00451
Short name=NDK HAMAP-Rule MF_00451
Short name=NDP kinase HAMAP-Rule MF_00451
EC=2.7.4.6 HAMAP-Rule MF_00451
Alternative name(s):
Nucleoside-2-P kinase HAMAP-Rule MF_00451
Gene names
Name:ndk HAMAP-Rule MF_00451
Ordered Locus Names:Shell_1639
OrganismStaphylothermus hellenicus (strain DSM 12710 / JCM 10830 / BK20S6-10-b1 / P8) [Complete proteome] [HAMAP]
Taxonomic identifier591019 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Staphylothermus ›

Protein attributes

Sequence length141 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. RuleBase RU004013 HAMAP-Rule MF_00451

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00451

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00451.

Sequence similarities

Belongs to the NDK family. HAMAP-Rule MF_00451 RuleBase RU004011

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1171Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451
Binding site111ATP By similarity HAMAP-Rule MF_00451
Binding site591ATP By similarity HAMAP-Rule MF_00451
Binding site871ATP By similarity HAMAP-Rule MF_00451
Binding site931ATP By similarity HAMAP-Rule MF_00451
Binding site1041ATP By similarity HAMAP-Rule MF_00451
Binding site1141ATP By similarity HAMAP-Rule MF_00451

Sequences

Sequence LengthMass (Da)Tools
D7DAC8 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 3B6CF06DFD08D8C5

FASTA14115,834
        10         20         30         40         50         60 
MSIERTLVLI KPDGVRRGLI GEIISRFERK GLKIKALKML WLTRDKAEEF YSVHRGKPFF 

        70         80         90        100        110        120 
ESLIEFMTSG PIIAMVLEGD MAISVVRKMI GPTDGREAPP GTIRGDYSLS KSQNVVHASD 

       130        140 
SPESAVREIG VIFKDDEIID W

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References

[1]"Complete sequence of Staphylothermus hellenicus DSM 12710."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Anderson I.J., Woyke T.
Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12710 / JCM 10830 / BK20S6-10-b1 / P8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002051 Genomic DNA. Translation: ADI32724.1.
RefSeqYP_003669623.1. NC_014205.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI32724; ADI32724; Shell_1639.
GeneID9234932.
KEGGshc:Shell_1639.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224564.
KOK00940.
OMAIARFERK.

Family and domain databases

Gene3D3.30.70.141. 1 hit.
HAMAPMF_00451. NDP_kinase.
InterProIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PANTHERPTHR11349. PTHR11349. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
PROSITEPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD7DAC8_STAHD
AccessionPrimary (citable) accession number: D7DAC8
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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