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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

Trad_0748

Organism
Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciTRAD649638:G1GKY-757-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:Trad_0748Imported
OrganismiTruepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)Imported
Taxonomic identifieri649638 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesTrueperaceaeTruepera
Proteomesi
  • UP000000379 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi649638.Trad_0748

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini177 – 214Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107QSN Bacteria
COG0508 LUCA
HOGENOMiHOG000281564
KOiK00627
OMAiDNLCEVQ
OrthoDBiPOG091H05OF

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

D7CTM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRELVLPEL AESVVEGEIV KWLVAEGETV AQDQPVVEVM TDKVTVELPS
60 70 80 90 100
PFAGTLEKHL VAEGAVVAVH DPIALFSDDA TGTQEAGATA EEAPKLEVAE
110 120 130 140 150
APTADAPPVT PTGREPSVQA REERSIVEPS SGVGEDDGDA LSLFKADKDD
160 170 180 190 200
PGAPVYQVRR GAAPQAAKAT GPYGRPLAVP AARKLARELG LELTAVAGSG
210 220 230 240 250
PHGRIRVEDV RRAAEASAPA AAEPPSAPAP TPKAPAYKTP AGYEGLEERV
260 270 280 290 300
PVRGLRRAIA NQMVASHLQT VRTLHVDEVD VTELVALRER LKPLAERRGV
310 320 330 340 350
KLSYLPFIMK AAVAALKRFP VLNASFDEER GEIVLKRFYN LGLAVATDVG
360 370 380 390 400
LVVPVVKDVD RKSVLEIAGE VSALAAKARE GKLAPEDVRG GTFSITNIGS
410 420 430 440 450
LGGLFSFPII NVPEAAILGV HSIKKRPVVL PDDTIAARQM LYLSLSFDHR
460 470
LVDGAEAAQF TSYVIELLGS PESLMLEG
Length:478
Mass (Da):50,610
Last modified:August 10, 2010 - v1
Checksum:i005A248B1EA69D4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002049 Genomic DNA Translation: ADI13883.1
RefSeqiWP_013177255.1, NC_014221.1

Genome annotation databases

EnsemblBacteriaiADI13883; ADI13883; Trad_0748
KEGGitra:Trad_0748

Similar proteinsi

Entry informationi

Entry nameiD7CTM6_TRURR
AccessioniPrimary (citable) accession number: D7CTM6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: March 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health