Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D7CR97

- D7CR97_TRURR

UniProt

D7CR97 - D7CR97_TRURR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thymidine kinase

Gene

tdk

Organism
Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei90 – 901Proton acceptorUniRule annotation
Metal bindingi146 – 1461ZincUniRule annotation
Metal bindingi149 – 1491ZincUniRule annotation
Metal bindingi184 – 1841ZincUniRule annotation
Metal bindingi187 – 1871ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 238ATPUniRule annotation
Nucleotide bindingi89 – 924ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTRAD649638:GH4M-2102-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Trad_2071Imported
OrganismiTruepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)Imported
Taxonomic identifieri649638 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesTrueperaceaeTruepera
ProteomesiUP000000379: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiTMRKTEE.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7CR97-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLFHPFRGGF LELIVGPMFS GKSEELIRRV TRAFIAKQRV QVFKPALDGR
60 70 80 90 100
YHAQAVASHN GRTLEALAVS DVEEMRAALS EAVQVVAIDE GQFLSAALVG
110 120 130 140 150
FACDLAESGK RVMIAGLDLD FRAEPFGPMP ELLSRAESVT KLTAVCVRCG
160 170 180 190 200
APATRTQRLI GGHPAHYDDP VILVGAAEAY EPRCRACHRV PRAERLTPLF

AESR
Length:204
Mass (Da):22,256
Last modified:August 10, 2010 - v1
Checksum:i26C1C07FC400C42E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002049 Genomic DNA. Translation: ADI15185.1.
RefSeqiWP_013178549.1. NC_014221.1.
YP_003705728.1. NC_014221.1.

Genome annotation databases

EnsemblBacteriaiADI15185; ADI15185; Trad_2071.
GeneIDi9281064.
KEGGitra:Trad_2071.
PATRICi38301290. VBITruRad72214_2042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002049 Genomic DNA. Translation: ADI15185.1 .
RefSeqi WP_013178549.1. NC_014221.1.
YP_003705728.1. NC_014221.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADI15185 ; ADI15185 ; Trad_2071 .
GeneIDi 9281064.
KEGGi tra:Trad_2071.
PATRICi 38301290. VBITruRad72214_2042.

Phylogenomic databases

HOGENOMi HOG000076390.
KOi K00857.
OMAi TMRKTEE.

Enzyme and pathway databases

BioCyci TRAD649638:GH4M-2102-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17093 / CIP 108686 / LMG 22925 / RQ-24Imported.

Entry informationi

Entry nameiD7CR97_TRURR
AccessioniPrimary (citable) accession number: D7CR97
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: November 26, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3