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D7CP25 (D7CP25_SYNLT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
Ordered Locus Names:Slip_1702
OrganismSyntrophothermus lipocalidus (strain DSM 12680 / TGB-C1) [Complete proteome] [HAMAP] EMBL ADI02460.1
Taxonomic identifier643648 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Syntrophomonadaceae › Syntrophothermus ›

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. SAAS SAAS000023 HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. SAAS SAAS000023 HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity SAAS SAAS000023 HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 255ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding154 – 1585ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding171 – 18717ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1271Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1851Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1871Magnesium By similarity HAMAP-Rule MF_00339
Binding site1621Substrate By similarity HAMAP-Rule MF_00339
Binding site2431Substrate By similarity HAMAP-Rule MF_00339
Binding site2491Substrate By similarity HAMAP-Rule MF_00339
Binding site2521Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
D7CP25 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: F2891275BA87B060

FASTA31934,048
        10         20         30         40         50         60 
MKKIAILTSG GDAPGMNAAV RAVVRAGIYA GYQVFGVTRG FQGLINGDFV EMTLGSVADI 

        70         80         90        100        110        120 
IHRGGTILRT SRCEEFMEEK GRLRGLEALR DAGIQDVIGI GGNGTIRGLY EFSKLGVNTV 

       130        140        150        160        170        180 
AIPGSIDNDI PYCDMSIGFD TAVNTVVSAI NRIRDTATAH ERIFIVEVMG RESGHIALTA 

       190        200        210        220        230        240 
GLAGGAESIL IPEVPFDLDQ VVERLKQGMK RGKLHSIIVV AEGCCGAYPL AREIQAKTGM 

       250        260        270        280        290        300 
DTKVTVLGHT QRGGMPSAMD RNLASRMGKR AVDLIVEGKG NMMTGYQGMK IVDVPLAQVI 

       310 
EGKKDIDLDI CEIARILSI

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002048 Genomic DNA. Translation: ADI02460.1.
RefSeqYP_003703025.1. NC_014220.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI02460; ADI02460; Slip_1702.
GeneID9274508.
KEGGslp:Slip_1702.
PATRIC38269916. VBISynLip21176_1762.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248870.
KOK00850.
OMAEFKTVEG.

Enzyme and pathway databases

BioCycSLIP643648:GHUR-1741-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD7CP25_SYNLT
AccessionPrimary (citable) accession number: D7CP25
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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