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D7CJF4 (D7CJF4_SYNLT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit K HAMAP-Rule MF_01456
EC=1.6.99.5 HAMAP-Rule MF_01456
Alternative name(s):
NADH dehydrogenase I subunit K HAMAP-Rule MF_01456
NDH-1 subunit K HAMAP-Rule MF_01456
Gene names
Name:nuoK HAMAP-Rule MF_01456
Ordered Locus Names:Slip_0256
OrganismSyntrophothermus lipocalidus (strain DSM 12680 / TGB-C1) [Complete proteome] [HAMAP] EMBL ADI01043.1
Taxonomic identifier643648 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Syntrophomonadaceae › Syntrophothermus ›

Protein attributes

Sequence length102 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity. HAMAP-Rule MF_01456

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity. HAMAP-Rule MF_01456

Catalytic activity

NADH + quinone = NAD+ + quinol. HAMAP-Rule MF_01456

Subunit structure

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity. HAMAP-Rule MF_01456

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01456.

Sequence similarities

Belongs to the complex I subunit 4L family. HAMAP-Rule MF_01456

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane2 – 2221Helical; By similarity HAMAP-Rule MF_01456
Transmembrane29 – 4921Helical; By similarity HAMAP-Rule MF_01456
Transmembrane63 – 8321Helical; By similarity HAMAP-Rule MF_01456

Sequences

Sequence LengthMass (Da)Tools
D7CJF4 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: ECB0C3D33CBB1DAE

FASTA10211,163
        10         20         30         40         50         60 
MIGLQHYLLL GTLLFGIGAY GVLAKRNAVA VLMSVELMLN AVNVNFIAVN RYVTPHEAIG 

        70         80         90        100 
QLIALFVIVV AAAEVAVGLA LIITVFRQRR SVNLDEFNLL KW

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002048 Genomic DNA. Translation: ADI01043.1.
RefSeqYP_003701608.1. NC_014220.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI01043; ADI01043; Slip_0256.
GeneID9273033.
KEGGslp:Slip_0256.
PATRIC38266880. VBISynLip21176_0271.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000066429.
KOK00340.
OMARNAIVIF.

Enzyme and pathway databases

BioCycSLIP643648:GHUR-266-MONOMER.

Family and domain databases

HAMAPMF_01456. NDH1_NuoK.
InterProIPR001133. NADH_UbQ_OxRdtase_chain4L/K.
[Graphical view]
PANTHERPTHR11434. PTHR11434. 1 hit.
PfamPF00420. Oxidored_q2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD7CJF4_SYNLT
AccessionPrimary (citable) accession number: D7CJF4
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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