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D7CAP1

- D7CAP1_STRBB

UniProt

D7CAP1 - D7CAP1_STRBB

Protein

Probable DNA ligase

Gene

ligB

Organism
Streptomyces bingchenggensis (strain BCW-1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei208 – 2081ATPUniRule annotation
    Active sitei210 – 2101N6-AMP-lysine intermediateUniRule annotation
    Binding sitei215 – 2151ATPUniRule annotation
    Binding sitei230 – 2301ATPUniRule annotation
    Binding sitei259 – 2591ATPUniRule annotation
    Binding sitei299 – 2991ATPUniRule annotation
    Binding sitei377 – 3771ATPUniRule annotation
    Binding sitei383 – 3831ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSBIN749414:GHKA-5530-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligBImported
    Synonyms:ligUniRule annotation
    Ordered Locus Names:SBI_05488Imported
    OrganismiStreptomyces bingchenggensis (strain BCW-1)Imported
    Taxonomic identifieri749414 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000000377: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000036008.
    KOiK01971.
    OMAiVPIVIPY.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D7CAP1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLAEVARTS REVAATSARS EKIAALARLL SRVEPAEAPV VITYLAGRLP    50
    QRRIGVGWAG LRVRPEPAAG PRLGVLDVHQ ALDRVAAVSG TGATTERKRL 100
    VSGLMSAATE DEQAFLFGLI GGELRQGALD ALAVEGLSAA VGAPPAEVRR 150
    AVMLGGSLGA VAQALLENGP PALSEFGLEV GRPVLPMLAH SARDLDEALD 200
    RLGPCAVEEK LDGIRVQVHR DKETVRVYTR TLDEITDRLP EVVAAARELA 250
    VERAVLDGEV IALDADGRPR PFQEISGRVG ARLDVAGASA SLPLYPVFFD 300
    LLAVDDRDLL DLSARDRHAE LARVAPAPRR VRRLVAEDPR DEATRRAARE 350
    FAADVLARGH EGVMAKSLDA PYSAGRRGAC WLKVKPVHTL DLVVLAAEWG 400
    HGRRTGKLSN LHLGARRPDG TYAMLGKTFK GLTDKQLGWQ TEALLRLAVS 450
    DDGWVVRVRP ELVVEVAFDS LQRSSRYPEG VTLRFARVLR YREDKPAEEA 500
    DTVETVLALR DA 512
    Length:512
    Mass (Da):55,292
    Last modified:August 10, 2010 - v1
    Checksum:i580406D4FD5B206D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002047 Genomic DNA. Translation: ADI08608.1.
    RefSeqiYP_004963739.1. NC_016582.1.

    Genome annotation databases

    EnsemblBacteriaiADI08608; ADI08608; SBI_05488.
    GeneIDi11609358.
    KEGGisbh:SBI_05488.
    PATRICi43268972. VBIStrBin158249_5667.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002047 Genomic DNA. Translation: ADI08608.1 .
    RefSeqi YP_004963739.1. NC_016582.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI08608 ; ADI08608 ; SBI_05488 .
    GeneIDi 11609358.
    KEGGi sbh:SBI_05488.
    PATRICi 43268972. VBIStrBin158249_5667.

    Phylogenomic databases

    HOGENOMi HOG000036008.
    KOi K01971.
    OMAi VPIVIPY.

    Enzyme and pathway databases

    BioCyci SBIN749414:GHKA-5530-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis."
      Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L., Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X., Xiang W.S.
      J. Bacteriol. 192:4526-4527(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BCW-1Imported.

    Entry informationi

    Entry nameiD7CAP1_STRBB
    AccessioniPrimary (citable) accession number: D7CAP1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3