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D7C8K9 (D7C8K9_STRBB) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Keywords
   Biological processDNA synthesis HAMAP-Rule MF_00124 SAAS SAAS020634
   Cellular componentCytoplasm HAMAP-Rule MF_00124
   LigandATP-binding HAMAP-Rule MF_00124 SAAS SAAS020634
Nucleotide-binding
   Molecular functionKinase HAMAP-Rule MF_00124 SAAS SAAS020634 EMBL ADI06398.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding86 – 894ATP By similarity HAMAP-Rule MF_00124

Sites

Active site871Proton acceptor By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
D7C8K9 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 7332DB8445E1DC16

FASTA23325,003
        10         20         30         40         50         60 
MPELVFFSGT MDCGKSTLAL QIEHNRSARG LQGMIYTRDD RAGRGKLSSR LGLVTEAVEA 

        70         80         90        100        110        120 
GDDLDFYAHV VGILTAGGRA DYVIVDEAQF LAPSQIDQLA RVVDDLGLDV FAFGITTDFR 

       130        140        150        160        170        180 
SKLFPGSQRL VELADRIEVL QVEALCWCGA RATHNARTVG GEMVVEGAQV VVGDVNQPGA 

       190        200        210        220        230 
EVGYEVLCRR HHRRRMTAAA ARAATLSPDV LPVDPAAAPA PVPHQAQTPR TAP 

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References

[1]"Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis."
Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L., Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X., Xiang W.S.
J. Bacteriol. 192:4526-4527(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BCW-1 EMBL ADI06398.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002047 Genomic DNA. Translation: ADI06398.1.
RefSeqYP_004961529.1. NC_016582.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI06398; ADI06398; SBI_03277.
GeneID11612431.
KEGGsbh:SBI_03277.
PATRIC43264378. VBIStrBin158249_3395.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000076391.
KOK00857.
OMAHYSTMNA.

Enzyme and pathway databases

BioCycSBIN749414:GHKA-3290-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD7C8K9_STRBB
AccessionPrimary (citable) accession number: D7C8K9
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)