D7C499 (D7C499_STRBB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inositol 2-dehydrogenase HAMAP-Rule MF_01671
EC=1.1.1.18 HAMAP-Rule MF_01671

Alternative name(s):
Myo-inositol 2-dehydrogenase HAMAP-Rule MF_01671

Gene names

Name:	iolG HAMAP-Rule MF_01671
Ordered Locus Names:	SBI_00800

Organism

Streptomyces bingchenggensis (strain BCW-1) [Complete proteome] [HAMAP] EMBL ADI03921.1

Taxonomic identifier

749414 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces › Streptomyces bingchenggensis

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP-Rule MF_01671
Catalytic activity	Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP-Rule MF_01671 SAAS SAAS023794
Subunit structure	Homotetramer By similarity. HAMAP-Rule MF_01671 SAAS SAAS023794
Sequence similarities	Belongs to the Gfo/Idh/MocA family. HAMAP-Rule MF_01671

Ontologies

Keywords
Ligand	NAD HAMAP-Rule MF_01671 SAAS SAAS023794
Molecular function	Oxidoreductase HAMAP-Rule MF_01671 SAAS SAAS023794
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	inositol 2-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D7C499 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: CF9BE6252E952A39	FASTA	339	36,141
	10 20 30 40 50 60 MTVRVGVIGA GMIGQDHIRR LTDVVTGAAV TAVTDIDQAR AAEVAATVGA VALPSGAELI 70 80 90 100 110 120 ASPEVDAVLV TSWGPTHAEH VLSAIAAGKP VFCEKPLATT AEDCLRIVDA ERALGRRLVQ 130 140 150 160 170 180 VGFMRRFDAG YRQMKEVIAA GSLGTPLIVH CAHRNPTVPD SYTSAMAAQD TAVHEIDVLR 190 200 210 220 230 240 WLLDDEIVSA QVITPRATGM RFEHLKDPQL MYFETANGVR IELEVFVNCQ YGYDIQCETV 250 260 270 280 290 300 GEKGLVRLPD PAAVGVRTAG AHGTAVPQDW KGRFADAFDT EFREWINGIA AGAEPTGPSA 310 320 330 WDGYAATVIT DAAVRSLESD SQVVTVDMKP RPAFYGGTA

References

[1]

"Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis." Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L., Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X., Xiang W.S. J. Bacteriol. 192:4526-4527(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BCW-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002047 Genomic DNA. Translation: ADI03921.1.
RefSeq	YP_004959052.1. NC_016582.1.
3D structure databases
ProteinModelPortal	D7C499.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADI03921; ADI03921; SBI_00800.
GeneID	11613836.
KEGG	sbh:SBI_00800.
PATRIC	43259202. VBIStrBin158249_0818.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000227439.
KO	K00010.
OMA	HINRITN.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
HAMAP	MF_01671. IolG.
InterPro	IPR023794. MI/DCI_dehydrogenase. IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR004104. OxRdtase_C. [Graphical view]
PANTHER	PTHR22604:SF7. PTHR22604:SF7. 1 hit.
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF02894. GFO_IDH_MocA_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D7C499_STRBB

Accession

Primary (citable) accession number: D7C499

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)