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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptomyces bingchenggensis (strain BCW-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei132 – 1321UniRule annotation
Active sitei564 – 5641UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSBIN749414:GHKA-4376-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SBI_04351Imported
OrganismiStreptomyces bingchenggensis (strain BCW-1)Imported
Taxonomic identifieri749414 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000000377: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7BTN2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSADNTNAA LRADIRRLGD LLGETLVRQE GPDLLDLVER VRALTRSDGE
60 70 80 90 100
AAAELLGDTD LETAAKLVRA FSTYFHLANI TEQVHRGREL RAKRAAEGGL
110 120 130 140 150
LSRTADQLKD ADPEHLREAV RHLNVRPVFT AHPTEAARRT VLNKLRRVAE
160 170 180 190 200
LLDTLAVGGD KRRTDLRLAE NIDLLWQTDE LRVARPEPAD EARNAIYYLD
210 220 230 240 250
ELHAGAVGDV LEDLSAELER VGAPLPATTR PLTFGTWIGG DRDGNPNVTP
260 270 280 290 300
QVTWDVLILQ HEHGITDALA IVDDLRAALS SSIRNSDASE ELLDSLQRDL
310 320 330 340 350
ELLPEISPRY KRLNAEEPYR LKATCVRQKL LNTRTRLAGG TPHQPGRDYL
360 370 380 390 400
GTAELLADLH LIQESLRAHR GRLIADGRME RAIRTLAAFG LQLATMDVRE
410 420 430 440 450
HADAHHHALG QLFDRLGEES WRYADMPRDS RRKLLAKELR SRRPLAPTPA
460 470 480 490 500
PLDAAGAKTL GVFHTISEAF ERFGPEIVES YIISMCQGSD DVFAAAVLAR
510 520 530 540 550
EAGLVDLHAG WAKIGIVPLL ETTEELKIAD QLLDDMLSDP SYRRLVALRG
560 570 580 590 600
DVQEVMLGYS DSSKFGGITT SQWEIHRAQR LLRDVAHRHG VRLRLFHGRG
610 620 630 640 650
GTVGRGGGPT HDAILAQPWG TLEGEIKVTE QGEVISDKYL VPSLARENLE
660 670 680 690 700
LTVAATLQAS ALHTAPRQSD EALAGWDAAM DTVSDAAHRA YRALVEDPDL
710 720 730 740 750
PAYFFASTPV DQLAELHLGS RPSRRPDSGA GLDGLRAIPW VFGWTQSRQI
760 770 780 790 800
VPGWFGVGSG LKAAREAGLD PALDEMHQHW HFFRNFLSNV EMTLAKTDLR
810 820 830 840 850
IARHYVDTLV PDELKHVFAT IEAEHELTVR EVLRITGETE LLDSNPVLKQ
860 870 880 890 900
TFHVRDAYLD PISYLQVSLL HRQRTAHEQG EAPDPLLARA LLLTVNGVAA

GLRNTG
Length:906
Mass (Da):100,251
Last modified:August 10, 2010 - v1
Checksum:i07E666B8197E8E7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002047 Genomic DNA. Translation: ADI07471.1.
RefSeqiYP_004962602.1. NC_016582.1.

Genome annotation databases

EnsemblBacteriaiADI07471; ADI07471; SBI_04351.
GeneIDi11606005.
KEGGisbh:SBI_04351.
PATRICi43266598. VBIStrBin158249_4497.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002047 Genomic DNA. Translation: ADI07471.1.
RefSeqiYP_004962602.1. NC_016582.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADI07471; ADI07471; SBI_04351.
GeneIDi11606005.
KEGGisbh:SBI_04351.
PATRICi43266598. VBIStrBin158249_4497.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciSBIN749414:GHKA-4376-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis."
    Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L., Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X., Xiang W.S.
    J. Bacteriol. 192:4526-4527(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BCW-1Imported.

Entry informationi

Entry nameiD7BTN2_STRBB
AccessioniPrimary (citable) accession number: D7BTN2
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: February 4, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.