D7BNV9 (D7BNV9_ARCHD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Triosephosphate isomerase HAMAP-Rule MF_00147
Short name=TIM HAMAP-Rule MF_00147
EC=5.3.1.1 HAMAP-Rule MF_00147

Alternative name(s):
Triose-phosphate isomerase HAMAP-Rule MF_00147

Gene names

Name:	tpiA HAMAP-Rule MF_00147
Ordered Locus Names:	Arch_0882

Organism

Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018) [Complete proteome] [HAMAP] EMBL ADH92608.1

Taxonomic identifier

644284 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Actinomycineae › Actinomycetaceae › Arcanobacterium › Arcanobacterium haemolyticum

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glyceraldehyde 3-phosphate = glycerone phosphate. SAAS SAAS020861 HAMAP-Rule MF_00147
Pathway	Carbohydrate biosynthesis; gluconeogenesis. SAAS SAAS020861 HAMAP-Rule MF_00147 RuleBase RU000517 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. SAAS SAAS020861 HAMAP-Rule MF_00147 RuleBase RU000517
Subunit structure	Homodimer By similarity. SAAS SAAS020861 HAMAP-Rule MF_00147
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00147.
Sequence similarities	Belongs to the triosephosphate isomerase family. HAMAP-Rule MF_00147 RuleBase RU004162

Ontologies

Keywords
Biological process	Gluconeogenesis RuleBase RU003527 SAAS SAAS020861 HAMAP-Rule MF_00147 Glycolysis SAAS SAAS020861 RuleBase RU003527 HAMAP-Rule MF_00147 Pentose shunt RuleBase RU003527 SAAS SAAS020861 HAMAP-Rule MF_00147
Cellular component	Cytoplasm HAMAP-Rule MF_00147
Molecular function	Isomerase SAAS SAAS020861 HAMAP-Rule MF_00147 RuleBase RU000517 EMBL ADH92608.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	triose-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	102	1	Electrophile By similarity HAMAP-Rule MF_00147
	Active site	174	1	Proton acceptor By similarity HAMAP-Rule MF_00147
	Binding site	10	1	Substrate By similarity HAMAP-Rule MF_00147
	Binding site	12	1	Substrate By similarity HAMAP-Rule MF_00147

Sequences

	Sequence		Length	Mass (Da)
	D7BNV9 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: 92B546D50378A8CD	FASTA	259	27,809
	10 20 30 40 50 60 MARTPIMAGN WKMNLDHLEA TALVQKLGWT LNDLKHDFSA VECVVVPPFT DIRSVQTLVD 70 80 90 100 110 120 SEDFKITYGA QDVSINDEGA FTGEISTGML TKLGVTYVVV GHSERREYHG ETNELIGKKA 130 140 150 160 170 180 KKVLDAGMTP IVCCGEALEI RKEGTHVEYV LGQIAAMFAD LSAEEVAKLV IAYEPIWAIG 190 200 210 220 230 240 TGEVATPADA QEVCGAIRGK IAEMFDAPTA EAVRIQYGGS VKSSNVVEIM AQPDVDGALV 250 GGASLKAEEF AKIVTFQQA

References

[1]

"Complete genome sequence of Arcanobacterium haemolyticum type strain (11018)." Yasawong M., Teshima H., Lapidus A., Nolan M., Lucas S., Glavina Del Rio T., Tice H., Cheng J., Bruce D., Detter C., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K., Mikhailova N. , Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Rohde M., Sikorski J., Pukall R., Goker M., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H. Stand. Genomic Sci. 3:126-135(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002045 Genomic DNA. Translation: ADH92608.1.
RefSeq	YP_003697227.1. NC_014218.1.
3D structure databases
ProteinModelPortal	D7BNV9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADH92608; ADH92608; Arch_0882.
GeneID	9261465.
KEGG	ahe:Arch_0882.
PATRIC	38110735. VBIArcHae78728_0863.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000226413.
KO	K01803.
OMA	QEVCGAI.
Enzyme and pathway databases
BioCyc	AHAE644284:GI54-913-MONOMER.
UniPathway	UPA00109; UER00189. UPA00138.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00147_B. TIM_B.
InterPro	IPR013785. Aldolase_TIM. IPR022896. TrioseP_Isoase_bac/euk. IPR000652. Triosephosphate_isomerase. IPR020861. Triosephosphate_isomerase_AS. [Graphical view]
PANTHER	PTHR21139. PTHR21139. 1 hit.
Pfam	PF00121. TIM. 1 hit. [Graphical view]
SUPFAM	SSF51351. Triophos_ismrse. 1 hit.
TIGRFAMs	TIGR00419. tim. 1 hit.
PROSITE	PS00171. TIM_1. 1 hit. PS51440. TIM_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D7BNV9_ARCHD

Accession

Primary (citable) accession number: D7BNV9

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)