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D7BNV9

- D7BNV9_ARCHD

UniProt

D7BNV9 - D7BNV9_ARCHD

Protein

Triosephosphate isomerase

Gene

tpiA

Organism
Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei10 – 101SubstrateUniRule annotation
    Binding sitei12 – 121SubstrateUniRule annotation
    Active sitei102 – 1021ElectrophileUniRule annotation
    Active sitei174 – 1741Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. triose-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP
    3. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    GluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation, Pentose shuntUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAHAE644284:GI54-914-MONOMER.
    UniPathwayiUPA00109; UER00189.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Triosephosphate isomeraseUniRule annotation (EC:5.3.1.1UniRule annotation)
    Short name:
    TIMUniRule annotation
    Alternative name(s):
    Triose-phosphate isomeraseUniRule annotation
    Gene namesi
    Name:tpiAUniRule annotation
    Ordered Locus Names:Arch_0882Imported
    OrganismiArcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018)Imported
    Taxonomic identifieri644284 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesActinomycineaeActinomycetaceaeArcanobacterium
    ProteomesiUP000000376: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD7BNV9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the triosephosphate isomerase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000226413.
    KOiK01803.
    OMAiYSKSAAD.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00147_B. TIM_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR022896. TrioseP_Isoase_bac/euk.
    IPR000652. Triosephosphate_isomerase.
    IPR020861. Triosephosphate_isomerase_AS.
    [Graphical view]
    PANTHERiPTHR21139. PTHR21139. 1 hit.
    PfamiPF00121. TIM. 1 hit.
    [Graphical view]
    SUPFAMiSSF51351. SSF51351. 1 hit.
    TIGRFAMsiTIGR00419. tim. 1 hit.
    PROSITEiPS00171. TIM_1. 1 hit.
    PS51440. TIM_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D7BNV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARTPIMAGN WKMNLDHLEA TALVQKLGWT LNDLKHDFSA VECVVVPPFT    50
    DIRSVQTLVD SEDFKITYGA QDVSINDEGA FTGEISTGML TKLGVTYVVV 100
    GHSERREYHG ETNELIGKKA KKVLDAGMTP IVCCGEALEI RKEGTHVEYV 150
    LGQIAAMFAD LSAEEVAKLV IAYEPIWAIG TGEVATPADA QEVCGAIRGK 200
    IAEMFDAPTA EAVRIQYGGS VKSSNVVEIM AQPDVDGALV GGASLKAEEF 250
    AKIVTFQQA 259
    Length:259
    Mass (Da):27,809
    Last modified:August 10, 2010 - v1
    Checksum:i92B546D50378A8CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002045 Genomic DNA. Translation: ADH92608.1.
    RefSeqiYP_003697227.1. NC_014218.1.

    Genome annotation databases

    EnsemblBacteriaiADH92608; ADH92608; Arch_0882.
    GeneIDi9261465.
    KEGGiahe:Arch_0882.
    PATRICi38110735. VBIArcHae78728_0863.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002045 Genomic DNA. Translation: ADH92608.1 .
    RefSeqi YP_003697227.1. NC_014218.1.

    3D structure databases

    ProteinModelPortali D7BNV9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADH92608 ; ADH92608 ; Arch_0882 .
    GeneIDi 9261465.
    KEGGi ahe:Arch_0882.
    PATRICi 38110735. VBIArcHae78728_0863.

    Phylogenomic databases

    HOGENOMi HOG000226413.
    KOi K01803.
    OMAi YSKSAAD.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00189 .
    UPA00138 .
    BioCyci AHAE644284:GI54-914-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00147_B. TIM_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR022896. TrioseP_Isoase_bac/euk.
    IPR000652. Triosephosphate_isomerase.
    IPR020861. Triosephosphate_isomerase_AS.
    [Graphical view ]
    PANTHERi PTHR21139. PTHR21139. 1 hit.
    Pfami PF00121. TIM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51351. SSF51351. 1 hit.
    TIGRFAMsi TIGR00419. tim. 1 hit.
    PROSITEi PS00171. TIM_1. 1 hit.
    PS51440. TIM_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018Imported.

    Entry informationi

    Entry nameiD7BNV9_ARCHD
    AccessioniPrimary (citable) accession number: D7BNV9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3