Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D7BHZ2

- D7BHZ2_MEISD

UniProt

D7BHZ2 - D7BHZ2_MEISD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene

Mesil_0325

Organism
Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei132 – 1321SubstrateUniRule annotation
Active sitei250 – 2501Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei305 – 3051Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMSIL526227:GJ9Q-332-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mesil_0325Imported
OrganismiMeiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus)Imported
Taxonomic identifieri526227 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus
ProteomesiUP000001916: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD7BHZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiRIGISIY.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7BHZ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPAWLEVNL DSLAHNVALL RSKAPASQLV GIVKANAYGH GAVWVGRELL
60 70 80 90 100
RLGAWGLAVA TVSEGRELRL GGVQGRVLLM GSLHPDQARE ALETDLIASL
110 120 130 140 150
STLEGAQALD AAARALGKIA EVHLEFDTGM GRVGFPWEEA QQVKEALEQF
160 170 180 190 200
SHLKVTGLYS HFADAEENLE FTYMQLANFR RVREVWGPGY FCHLANSAGV
210 220 230 240 250
FNFRDDSFDA IRPGIALYGL LPNLGLKPIA RLLAKPTLVK QLPPGRKIGY
260 270 280 290 300
SGLYTTQDHE WIATLPVGYA DGMPRLVYNR ATVRLLQPSP EEGRLICPVV
310 320 330 340 350
GRISMDQITV RIPGPVDLDT VFEVVTADFD PGSSLWGWAE MTGTVSYEPA
360 370
VRLAARLPRV YLRGGVEVAR IEP
Length:373
Mass (Da):40,828
Last modified:August 10, 2010 - v1
Checksum:i690644AF205FB535
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002042 Genomic DNA. Translation: ADH62266.1.
RefSeqiYP_003683774.1. NC_014212.1.

Genome annotation databases

EnsemblBacteriaiADH62266; ADH62266; Mesil_0325.
GeneIDi9249807.
KEGGimsv:Mesil_0325.
PATRICi38189346. VBIMeiSil18825_0339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002042 Genomic DNA. Translation: ADH62266.1 .
RefSeqi YP_003683774.1. NC_014212.1.

3D structure databases

ProteinModelPortali D7BHZ2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADH62266 ; ADH62266 ; Mesil_0325 .
GeneIDi 9249807.
KEGGi msv:Mesil_0325.
PATRICi 38189346. VBIMeiSil18825_0339.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi RIGISIY.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci MSIL526227:GJ9Q-332-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700542 / DSM 9946 / VI-R2Imported.

Entry informationi

Entry nameiD7BHZ2_MEISD
AccessioniPrimary (citable) accession number: D7BHZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: October 29, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3