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D7BFL4 (D7BFL4_MEISD) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Mesil_1684 EMBL ADH63567.1
OrganismMeiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus) [Complete proteome] [HAMAP] EMBL ADH63567.1
Taxonomic identifier526227 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus

Protein attributes

Sequence length425 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
D7BFL4 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: FEA8093EE8BB1A47

FASTA42546,622
        10         20         30         40         50         60 
MAYKHIQVPE GEKITIQNGQ LQVPDRPILG FIEGDGTGPD IWRASQPVLD AAVEKAYGGK 

        70         80         90        100        110        120 
KKIAWTEIYA GEKANAVYGE AVWLPEETLD FIREYRVAIK GPLTTPVGGG IRSINVALRQ 

       130        140        150        160        170        180 
ELDLYACVRP VQWFEGVPSP VRHPELVNMV IFRENTEDIY AGIEWAAGTS EAKKLLEFLK 

       190        200        210        220        230        240 
AEFPKAYGKI RFPETAGVGI KPISQEGTYR LVEAAINYAI ANNLPSVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GAFRDWGYRL AKEKYGAQDL DGSPWQILKN PRTGGDIVIK DMIADNFLQQ ILLRPAEYSV 

       310        320        330        340        350        360 
VATPNLNGDY LSDALAAQVG GIGIAPGANI NYYTGHAVFE ATHGTAPKYA GKDQVNPSSV 

       370        380        390        400        410        420 
ILSGEMMLRY LGWTEAADLI LSAMTKTIAQ GRVTYDFHRL MVAEGRPATL LKCSEFGQAL 


VENMG 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002042 Genomic DNA. Translation: ADH63567.1.
RefSeqYP_003685075.1. NC_014212.1.

3D structure databases

ProteinModelPortalD7BFL4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADH63567; ADH63567; Mesil_1684.
GeneID9251190.
KEGGmsv:Mesil_1684.
PATRIC38192167. VBIMeiSil18825_1727.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.

Enzyme and pathway databases

BioCycMSIL526227:GJ9Q-1715-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD7BFL4_MEISD
AccessionPrimary (citable) accession number: D7BFL4
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 14, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)