D7BEE6 (D7BEE6_MEISD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase EMBL ADH63189.1
EC=1.1.1.42 EMBL ADH63189.1

Gene names

Ordered Locus Names:

Mesil_1295

Organism

Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus) [Complete proteome] [HAMAP]

Taxonomic identifier

526227 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Meiothermus › Meiothermus silvanus

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444 EMBL ADH63189.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glyoxylate cycle Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D7BEE6 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: 8459FC418498A654	FASTA	480	53,106
	10 20 30 40 50 60 MSKTPITVAY GDGIGPEIME AVLKILDAAQ ARIAPEVIEI GESVYLRGHT SGIEESAWES 70 80 90 100 110 120 LRRTKVFLKA PITTPRGGGY KSLNVTVRKT LGLYANVRPV QSYEPFVTTK HKSIDLVIVR 130 140 150 160 170 180 ENEEDLYAGI EHQQTDEVVQ CLKLISRPGT ERIVRYAYEF ARRNGCRKIT CITKDNIMKL 190 200 210 220 230 240 TDGLFHRVFD EVGQEYPELQ KEHMIVDIGA ARLAEMPERF DVILAPNLYG DILSDIAAEV 250 260 270 280 290 300 AGSVGLAGSA NVGDEVAMFE AVHGSAPDIA GKGIANPSGL LQGAILMLVH IGQSEVAARI 310 320 330 340 350 360 KNAWLKTLED GIHTPDIYDE RVSEKKVGTQ EFAQAVIERL GQEPERLRPA RFGKPSPEPM 370 380 390 400 410 420 VPKLERKTPA QKELVGVDVF FNWRGQKPEE LAAMLEPLAG QNLELVMITN RGVKVWPGGF 430 440 450 460 470 480 PETFRTDHWR GRFMGQGREV RHSDVVALLG RLAEAGLDFI KTEHLYTFDG KPGYSLGQGQ

References

[1]

"Complete genome sequence of Meiothermus silvanus type strain (VI-R2)." Sikorski J., Tindall B., Lowry S., Lucas S., Nolan M., Copeland A., Glavina Del Rio T., Tice H., Cheng J., Han C., Pitluck S., Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Goodwin L., Chen A. , Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Rohde M., Goker M., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H., Lapidus A. Stand. Genomic Sci. 3:37-46(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700542 / DSM 9946 / VI-R2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002042 Genomic DNA. Translation: ADH63189.1.
RefSeq	YP_003684697.1. NC_014212.1.
3D structure databases
ProteinModelPortal	D7BEE6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADH63189; ADH63189; Mesil_1295.
GeneID	9250791.
KEGG	msv:Mesil_1295.
PATRIC	38191346. VBIMeiSil18825_1327.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000021113.
KO	K00031.
OMA	ANYGRDY.
Enzyme and pathway databases
BioCyc	MSIL526227:GJ9Q-1316-MONOMER.
Family and domain databases
Gene3D	3.40.718.10. 1 hit.
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR001804. Isocitrate/isopropylmalate_DH. IPR014273. Isocitrate_DH_aproteobac-typ. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
PANTHER	PTHR11835. PTHR11835. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR02924. ICDH_alpha. 1 hit.
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D7BEE6_MEISD

Accession

Primary (citable) accession number: D7BEE6

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)