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Protein
Submitted name:

Proline dehydrogenase

Gene

Mesil_3124

Organism
Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei99SubstrateUniRule annotation1
Binding sitei134FADUniRule annotation1
Binding sitei163FADUniRule annotation1
Binding sitei201FADUniRule annotation1
Binding sitei288SubstrateUniRule annotation1
Binding sitei289SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi187 – 189FADUniRule annotation3
Nucleotide bindingi226 – 227FADUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandFADUniRule annotation, Flavoprotein, Nucleotide-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMSIL526227:GJ9Q-3060-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Proline dehydrogenaseImported
Gene namesi
Ordered Locus Names:Mesil_3124Imported
OrganismiMeiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus silvanus)Imported
Taxonomic identifieri526227 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMeiothermus
Proteomesi
  • UP000001916 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi526227.Mesil_3124.

Structurei

3D structure databases

ProteinModelPortaliD7BE97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 300Pro_dhInterPro annotationAdd BLAST256

Phylogenomic databases

eggNOGiENOG41062BK. Bacteria.
COG0506. LUCA.
HOGENOMiHOG000019712.
KOiK00318.
OMAiPYGRDWY.
OrthoDBiPOG091H0AS4.

Family and domain databases

Gene3Di3.20.20.220. 1 hit.
InterProiView protein in InterPro
IPR029041. FAD-linked_oxidoreductase-like.
IPR008219. PRODH_bac_arc.
IPR002872. Proline_DH_dom.
PfamiView protein in Pfam
PF01619. Pro_dh. 1 hit.
PIRSFiPIRSF000196. Pro_dehydrog. 1 hit.
SUPFAMiSSF51730. SSF51730. 1 hit.

Sequencei

Sequence statusi: Complete.

D7BE97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLNLSYRSF VLAIAQNPSV KNLVLTRGKG LSRRFVAGDT LEEALKVVEG
60 70 80 90 100
LERERIHAIL DLLGEMVTSE EMARGFQAEI VGLIRALGAR PYPRYVSVKL
110 120 130 140 150
TQLGLDLSED LAFSLMQGIL QEARQADCFV RIDMEDSPRV DATLRVYRRL
160 170 180 190 200
REEGYTHTGI VLQSYLKRSE KDLEALLPLK PAVRIVKGAY KEPPEVAFQD
210 220 230 240 250
KRLIDAQYLL LAKKALENGL PTAIATHDPH LIAEMQRWTA EKGISKEGFE
260 270 280 290 300
FQLLYGVRRD EQRRLAAEGY TVRAYVPYGT DWYPYLSRRI AERPENLLFV

ARSLVQG
Length:307
Mass (Da):34,895
Last modified:August 10, 2010 - v1
Checksum:i50E3CA5E6644FBF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002042 Genomic DNA. Translation: ADH64955.1.
RefSeqiWP_013159483.1. NC_014212.1.

Genome annotation databases

EnsemblBacteriaiADH64955; ADH64955; Mesil_3124.
KEGGimsv:Mesil_3124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002042 Genomic DNA. Translation: ADH64955.1.
RefSeqiWP_013159483.1. NC_014212.1.

3D structure databases

ProteinModelPortaliD7BE97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi526227.Mesil_3124.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADH64955; ADH64955; Mesil_3124.
KEGGimsv:Mesil_3124.

Phylogenomic databases

eggNOGiENOG41062BK. Bacteria.
COG0506. LUCA.
HOGENOMiHOG000019712.
KOiK00318.
OMAiPYGRDWY.
OrthoDBiPOG091H0AS4.

Enzyme and pathway databases

BioCyciMSIL526227:GJ9Q-3060-MONOMER.

Family and domain databases

Gene3Di3.20.20.220. 1 hit.
InterProiView protein in InterPro
IPR029041. FAD-linked_oxidoreductase-like.
IPR008219. PRODH_bac_arc.
IPR002872. Proline_DH_dom.
PfamiView protein in Pfam
PF01619. Pro_dh. 1 hit.
PIRSFiPIRSF000196. Pro_dehydrog. 1 hit.
SUPFAMiSSF51730. SSF51730. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD7BE97_MEISD
AccessioniPrimary (citable) accession number: D7BE97
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 7, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.