Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D7B7P7

- D7B7P7_NOCDD

UniProt

D7B7P7 - D7B7P7_NOCDD

Protein

Alanine racemase

Gene

Ndas_4045

Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei133 – 1331SubstrateUniRule annotation
    Active sitei264 – 2641Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei312 – 3121Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciNDAS446468:GHUM-4091-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Ndas_4045Imported
    OrganismiNocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)Imported
    Taxonomic identifieri446468 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeNocardiopsaceaeNocardiopsis
    ProteomesiUP000002219: Chromosome 1

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD7B7P7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiGHTWTAQ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D7B7P7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHFAHARVD LDAISHNARV LRGFAGGTPL MGVVKADGYG HGMLPAARAL    50
    IAGGATWLGT AFIGEALELR RAGLTPPVLA WIIPPGEPVA EAVEADIDLG 100
    VSDRAVLDTV IAEARRIGRT ARVQLKADTG LNRGGVGPAD WGALAEAAAR 150
    AEDEGHLRVT GVWSHFACAD EPGHPSVARQ LSRFHEALET ADKVGLTPEV 200
    RHIANSAALL TLPEARFDLV RGGIASYGLS PIPGLTGTGL RPAMTLRSRL 250
    ALTKRVPEGS GVSYGHRYVT DRETTLALVP LGYADGVPRA ATNRGPVLLG 300
    GRRRAVAGTV CMDQFVVDVG DDAVEAGEYA VLFGNPEDHP DTPTAEDWAE 350
    ILDTIPYEIV TRVGPRVPRE YVGGGA 376
    Length:376
    Mass (Da):39,531
    Last modified:August 10, 2010 - v1
    Checksum:i41F76288EB34F862
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002040 Genomic DNA. Translation: ADH69442.1.
    RefSeqiYP_003681948.1. NC_014210.1.

    Genome annotation databases

    EnsemblBacteriaiADH69442; ADH69442; Ndas_4045.
    GeneIDi9247917.
    KEGGinda:Ndas_4045.
    PATRICi38218201. VBINocDas52663_4203.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002040 Genomic DNA. Translation: ADH69442.1 .
    RefSeqi YP_003681948.1. NC_014210.1.

    3D structure databases

    ProteinModelPortali D7B7P7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADH69442 ; ADH69442 ; Ndas_4045 .
    GeneIDi 9247917.
    KEGGi nda:Ndas_4045.
    PATRICi 38218201. VBINocDas52663_4203.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi GHTWTAQ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci NDAS446468:GHUM-4091-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488Imported.

    Entry informationi

    Entry nameiD7B7P7_NOCDD
    AccessioniPrimary (citable) accession number: D7B7P7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3