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D7B745

- D7B745_NOCDD

UniProt

D7B745 - D7B745_NOCDD

Protein

Thymidine kinase

Gene

Ndas_0149

Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciNDAS446468:GHUM-154-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Ordered Locus Names:Ndas_0149Imported
    OrganismiNocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)Imported
    Taxonomic identifieri446468 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeNocardiopsaceaeNocardiopsis
    ProteomesiUP000002219: Chromosome 1

    Structurei

    3D structure databases

    ProteinModelPortaliD7B745.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000076391.
    KOiK00857.
    OMAiQNARIED.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D7B745-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAELKYFTGS MNSGKSTMAL QEHHSRGGEG VLYTKQDRAG AGIISSRLGL    50
    ESPAVEVGDD LDLYDDIADR KAPYVICDEA QFLSYKQVGQ LAGVVDGMRI 100
    DVYCYGILTD FQGQLFPGSK RLVELADKIE VLPVSARCWC GGRATHNARV 150
    VDGVMIYEGE QVHIGGNESY ATLCRHHFMA GVA 183
    Length:183
    Mass (Da):19,925
    Last modified:August 10, 2010 - v1
    Checksum:i732DB459AB49BE99
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002040 Genomic DNA. Translation: ADH65599.1.
    RefSeqiYP_003678105.1. NC_014210.1.

    Genome annotation databases

    EnsemblBacteriaiADH65599; ADH65599; Ndas_0149.
    GeneIDi9243980.
    KEGGinda:Ndas_0149.
    PATRICi38210028. VBINocDas52663_0156.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002040 Genomic DNA. Translation: ADH65599.1 .
    RefSeqi YP_003678105.1. NC_014210.1.

    3D structure databases

    ProteinModelPortali D7B745.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADH65599 ; ADH65599 ; Ndas_0149 .
    GeneIDi 9243980.
    KEGGi nda:Ndas_0149.
    PATRICi 38210028. VBINocDas52663_0156.

    Phylogenomic databases

    HOGENOMi HOG000076391.
    KOi K00857.
    OMAi QNARIED.

    Enzyme and pathway databases

    BioCyci NDAS446468:GHUM-154-MONOMER.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488Imported.

    Entry informationi

    Entry nameiD7B745_NOCDD
    AccessioniPrimary (citable) accession number: D7B745
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3