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D7B745

- D7B745_NOCDD

UniProt

D7B745 - D7B745_NOCDD

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Protein

Thymidine kinase

Gene
Ndas_0149
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciNDAS446468:GHUM-154-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Ndas_0149Imported
OrganismiNocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) (Actinomadura dassonvillei)Imported
Taxonomic identifieri446468 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeNocardiopsaceaeNocardiopsis
ProteomesiUP000002219: Chromosome 1

Structurei

3D structure databases

ProteinModelPortaliD7B745.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391.
KOiK00857.
OMAiQNARIED.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7B745-1 [UniParc]FASTAAdd to Basket

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MAELKYFTGS MNSGKSTMAL QEHHSRGGEG VLYTKQDRAG AGIISSRLGL    50
ESPAVEVGDD LDLYDDIADR KAPYVICDEA QFLSYKQVGQ LAGVVDGMRI 100
DVYCYGILTD FQGQLFPGSK RLVELADKIE VLPVSARCWC GGRATHNARV 150
VDGVMIYEGE QVHIGGNESY ATLCRHHFMA GVA 183
Length:183
Mass (Da):19,925
Last modified:August 10, 2010 - v1
Checksum:i732DB459AB49BE99
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002040 Genomic DNA. Translation: ADH65599.1.
RefSeqiYP_003678105.1. NC_014210.1.

Genome annotation databases

EnsemblBacteriaiADH65599; ADH65599; Ndas_0149.
GeneIDi9243980.
KEGGinda:Ndas_0149.
PATRICi38210028. VBINocDas52663_0156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002040 Genomic DNA. Translation: ADH65599.1 .
RefSeqi YP_003678105.1. NC_014210.1.

3D structure databases

ProteinModelPortali D7B745.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADH65599 ; ADH65599 ; Ndas_0149 .
GeneIDi 9243980.
KEGGi nda:Ndas_0149.
PATRICi 38210028. VBINocDas52663_0156.

Phylogenomic databases

HOGENOMi HOG000076391.
KOi K00857.
OMAi QNARIED.

Enzyme and pathway databases

BioCyci NDAS446468:GHUM-154-MONOMER.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488.

Entry informationi

Entry nameiD7B745_NOCDD
AccessioniPrimary (citable) accession number: D7B745
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 14, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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