ID   D7AQL6_THEM3            Unreviewed;       325 AA.
AC   D7AQL6;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=D-alanine--D-alanine ligase {ECO:0000313|EMBL:ADH59902.1};
DE            EC=6.3.2.4 {ECO:0000313|EMBL:ADH59902.1};
GN   OrderedLocusNames=Tmath_0117 {ECO:0000313|EMBL:ADH59902.1};
OS   Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CCUG
OS   53645 / CIP 108742 / A3).
OC   Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Thermoanaerobacter.
OX   NCBI_TaxID=583358 {ECO:0000313|EMBL:ADH59902.1, ECO:0000313|Proteomes:UP000002064};
RN   [1] {ECO:0000313|EMBL:ADH59902.1, ECO:0000313|Proteomes:UP000002064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11426 / CIP 108742 / A3
RC   {ECO:0000313|Proteomes:UP000002064};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Zhou J., Hemme C., Woyke T.;
RT   "Complete sequence of Thermoanaerobacter mathranii subsp. mathranii
RT   mathranii str. A3.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
CC       {ECO:0000256|ARBA:ARBA00010871}.
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DR   EMBL; CP002032; ADH59902.1; -; Genomic_DNA.
DR   AlphaFoldDB; D7AQL6; -.
DR   STRING; 583358.Tmath_0117; -.
DR   KEGG; tmt:Tmath_0117; -.
DR   HOGENOM; CLU_039268_2_0_9; -.
DR   Proteomes; UP000002064; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR011095; Dala_Dala_lig_C.
DR   PANTHER; PTHR23132; D-ALANINE--D-ALANINE LIGASE; 1.
DR   PANTHER; PTHR23132:SF0; D-ALANINE-D-ALANINE LIGASE FAMILY; 1.
DR   Pfam; PF07478; Dala_Dala_lig_C; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADH59902.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT   DOMAIN          105..316
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   325 AA;  37177 MW;  E1D790FF04FD031D CRC64;
     MKIGVLWRKF RNVEFQRKLM PDKVYDDAYD EAYHHYMAIK EAGFDSVLIE WKEDPLETYE
     TIKKEKVDLI FNASSMKEVA FLEVFNIPYV GSGLDLVATD KRMRKDIVAF HGLPTPKYVV
     AKNSQEIPPV GHLRFPLFVK PISGRGSAGI DEENIVYDKD KLPQVVRKIT EKIGQAALIE
     EFIEGKEVTV GIIGYKHPQV LPLLEVGYNN VKTNTYEHKM FDNEIIKCPM EVSKEVEEKI
     KETALNIYKV LNAKDFARID MILSKDNVPY FLELNTFAGL TMSSSKGEKH VHHGYMGYMA
     KAAGLTRGEF IGKIIESAIE RYKLK
//